The critical involvement of GPCRs (G-protein-coupled receptors) in nearly all physiological
processes, and the presence of these receptors at the interface between the extracellular …

The great versatility of G protein-coupled receptors (GPCRs), in terms of both their ability to
bind different types of ligands and initiate a large number of distinct cellular signaling events …

Communication between cells requires key and specialized signaling systems, like G-
protein-coupled receptors (GPCRs). Cells coexpress a large number of different GPCRs, the …

G Protein Coupled Receptors (GPCRs) represent the largest family of membrane proteins in
the human genome, are the targets of approximately 25% of all marketed pharmaceuticals …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …

The discovery of biased signaling at G protein-coupled receptors (GPCRs), the largest class
of cell surface receptors and primary drug targets for numerous human diseases, has …

G protein coupled receptors (GPCRs) are an important class of ligand-activated proteins that
regulate cellular metabolism. It is now appears that GPCR function is highly dependent upon …

With> 800 members, G protein-coupled receptors (GPCRs) are the largest class of cell-
surface signalling proteins, and their activation mediates diverse physiological processes …

G protein-coupled receptors (GPCRs), which are modulated by a variety of endogenous and
synthetic ligands, represent the largest family of druggable targets in the human genome …

The traditional view on GPCRs held that they function as single monomeric units composed
of identical subunits. This notion was overturned by the discovery that GPCRs can form …