Chronic neuroinflammation is an important factor in the development of neuropathic pain
(NP). Excess microglia activation releases a mass of pro-inflammatory cytokines during …

Hypersensitivity to mechanical stimulation is a well documented symptom of neuropathic
pain, for which there is currently no effective therapy. Src-family kinases (SFKs) are involved …

Background Lumbar disc herniation is a major cause of radicular pain, but the underlying
mechanisms remain largely unknown. Spinal activation of src-family kinases are involved in …

Chronic neuroinflammation is of great importance in the pathogenesis of Parkinson's
disease (PD). During the process of neuroinflammation, overactivated microglia release …

Protein tyrosine phosphorylation has been implicated in normal and pathological functions
such as cell proliferation, migration and differentiation. Recently, some studies have shown …

Neuroinflammation plays an important role in the induction and maintenance of chronic
pain. Orchestra of pattern-recognition receptor-induced pro-inflammatory and anti …

We evaluated the mechanisms underlying the spinal cord stimulation (SCS)-induced
analgesic effect on neuropathic pain following spared nerve injury (SNI). On day 3 after SNI …

Study Design. A controlled, randomized, animal study. Objective. The aim of this study was
to investigate the role of src-family kinases/p38 pathway in a rat model of lumbar disc …

Although microglia activation plays an important role in the development of nerve injury-
induced neuropathic pain, the molecular mechanisms of spinal cord microglia activation in …

Introduction Neuropathic pain is a debilitating condition. The importance of neuroimmune
interactions in neuropathic pain has been evidenced by the involvement of different immune …