Research on the formation of novel enzymatic oxygenation products derived from the ω-3
fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) has revealed the …

A well-integrated inflammatory response and its natural resolution are essential to
homeostasis. Hence, it is important to achieve a complete understanding of the molecular …

Acute inflammation, the primary response to harmful infection and injury, can be successfully
completed through effective resolution and tissue repair. Resolution of inflammation requires …

Inflammation is the first response of the immune system to infection or injury, but excessive
or inappropriate inflammatory responses contribute to a range of acute and chronic human …

Resolution of inflammation has historically been viewed as a passive process, occurring as
a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as …

Cardiovascular disease (CVD) represents a global burden with a prevalence that continues
increasing progressively. CVD comprises a group of disorders of the heart and blood …

Using a systems approach to mine spontaneously resolving inflammatory exudates, novel
families of lipid-derived mediators were identified in animal systems that control both the …

Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived
molecules which play important roles in the resolution of inflammation. They are termed …

The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …

The n-3 polyunsaturated fatty acids eicosapentaenoic acid, docosahexaenoic acid and n-3
docosapentaenoic acid, act as substrates for the biosynthesis of specialized pro-resolving …