SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …

The pluripotency-associated transcription factor SOX2 is essential during mammalian
embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

SOX2 is a well-characterized pluripotent factor that is essential for stem cell self-renewal,
reprogramming, and homeostasis. The cellular levels of SOX2 are precisely regulated by a …

The transcription factor SOX2 is essential for embryonic development and plays a crucial
role in maintaining the stemness of embryonic cells and various adult stem cell populations …

Sox4, Sox11 and Sox12 constitute the group C of Sry-related HMG box proteins. They are co-
expressed in embryonic neuronal progenitors and in mesenchymal cells in many …

Transcriptional and epigenetic embryonic programs can be reactivated in cancer cells. As
result, a specific subset of undifferentiated cells with stem‐cells properties emerges and …

Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

SOX4 is a critical developmental transcription factor in vertebrates and is required for
precise differentiation and proliferation in multiple tissues. In addition, SOX4 is …

Introduction: SOX2 is a transcription factor that is important in the development and
maintenance of the stem cell state. Furthermore, SOX2 is associated with cancer …