The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and
metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid …

Although the brain lacks conventional lymphatic vessels found in peripheral tissue, evidence
suggests that the space surrounding the vasculature serves a similar role in the clearance of …

Formulated as a group effort of the stroke community, the transforming concept of the
neurovascular unit (NVU) depicts the structural and functional relationship between brain …

Perivascular spaces (PVS) and blood–brain barrier (BBB) disruption are two key features of
cerebral small vessel disease (cSVD) and neurodegenerative diseases that have been …

The brain is one of the most metabolically demanding organs—it requires 20% of the body's
energy supply yet forms only 2% of the body's weight. Therefore, brain activity is supported …

Pathophysiology of the neurovascular unit (NVU) is commonly seen in neurological
diseases. The typical features of NVU pathophysiology include tissue hypoxia, inflammatory …

In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Cerebral white matter lesions (WML) represent a spectrum of age-related structural changes
that are identified as areas of white matter high signal intensity on brain magnetic resonance …

Deleterious inflammatory cell invasion has been implicated in neurological diseases, partly
manifesting as a leaky blood-central nervous system barrier (BCNSB)(Huang et al., 2021) …

The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …