[HTML][HTML] Safety and efficacy of Paxlovid against Omicron variants of coronavirus disease 2019 in elderly patients

C Weng, R Xie, G Han, Y Yuan, S Li, C Wang… - Infectious Diseases and …, 2023 - Springer
Introduction Elderly patients are the most affected and vulnerable to COVID-19 and effective
therapeutic interventions are urgently required. We clarified the safety and efficacy of …

[HTML][HTML] The efficacy of paxlovid in elderly patients infected with SARS-CoV-2 omicron variants: Results of a non-randomized clinical trial

W Zhong, X Jiang, X Yang, T Feng, Z Duan… - Frontiers in …, 2022 - frontiersin.org
Objective: To evaluate the efficacy of Paxlovid in treating Chinese elder patients infected
with SARS-CoV-2 omicron variants. Methods: We performed a non-randomized, controlled …

Appraisal of evidence reliability and applicability of Paxlovid as treatment for SARS‐COV‐2 infection: A systematic review

C Zhu, JY Yin, X Chen, M Liu… - Reviews in Medical …, 2023 - Wiley Online Library
This study aimed to clarify the beneficial effect and the clinical application value of Paxlovid
in the treatment of coronavirus disease‐19 (COVID‐19) through a systematic review …

[HTML][HTML] Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study

J Liu, X Pan, S Zhang, M Li, K Ma, C Fan… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Nirmatrelvir plus ritonavir (Paxlovid) reduced the risk of
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …

[HTML][HTML] Effectiveness of paxlovid, an oral antiviral drug, against the Omicron BA. 5 variant in Korea: severe progression and death between July and November 2022

JM Kim, MG Yoo, SJ Bae, J Kim… - Journal of Korean Medical …, 2023 - ncbi.nlm.nih.gov
Background Paxlovid is an oral antiviral drug that received emergency use authorization in
South Korea for the treatment of patients with mild-to-moderate coronavirus disease 2019 …

Effectiveness of Paxlovid in reducing severe coronavirus disease 2019 and mortality in high-risk patients

R Najjar-Debbiny, N Gronich, G Weber… - Clinical Infectious …, 2023 - academic.oup.com
Background Paxlovid was granted an Emergency Use Authorization for the treatment of mild
to moderate coronavirus disease 2019 (COVID-19), based on the interim analysis of the …

[HTML][HTML] Early administration of Paxlovid reduces the viral elimination time in patients infected with SARS‐CoV‐2 Omicron variants

Y Wang, D Zhao, X Liu, X Chen, W Xiao… - Journal of Medical …, 2023 - ncbi.nlm.nih.gov
To the Editor, Nirmatrelvir/ritonavir (Paxlovid) is an oral antiviral drug that has been shown to
reduce the risk of hospitalization, severe COVID‐19, and mortality among mild‐to‐moderate …

In the age of Omicron variant: Paxlovid raises new hopes of COVID‐19 recovery.

Z Wang, L Yang - Journal of medical virology, 2022 - search.ebscohost.com
Since the outbreak of COVID-19, caused by the SARS-CoV-2, in December 2019, the
ongoing pandemic has posed 5 318 216 deaths worldwide. 1 Vaccines, traditional Chinese …

[HTML][HTML] Paxlovid: A promising drug for the challenging treatment of SARS-COV-2 in the pandemic era

N Niraj, SS Mahajan, A Prakash… - Indian Journal of …, 2022 - journals.lww.com
Coronavirus infection is a pandemic threat and the most dangerous disease of the 21 st
century. Despite the rigorous exertion of world-class researchers, there is no perfect cure for …

[HTML][HTML] Clinical progression and outcome of hospitalized patients infected with SARS-CoV-2 omicron variant in Shanghai, China

J Shao, R Fan, J Hu, T Zhang, C Lee, X Huang, F Wang… - Vaccines, 2022 - mdpi.com
Background: Studies on the Omicron variant infection have generally been restricted to
descriptions of its initial clinical and epidemiological characteristics. We investigated the …