The growing prevalence of antibiotic resistance calls for new approaches in the
development of antimicrobial therapeutics. Likewise, improved diagnostic measures are …

The rising prevalence of antibiotic resistant microbial pathogens presents an ominous health
and economic challenge to modern society. The discovery and large-scale development of …

Lack of pathogen specificity in antimicrobial therapy causes non-discriminant microbial cell
killing that disrupts the microflora present. As a result, potentially helpful microbial cells are …

Highlights•Multidrug-resistant infections have sparked a renewed interest in
bacteriophages.•Synthetic biology has enabled technologies for next-generation phage …

Synthetic biology is a relatively new field with the key aim of designing and constructing
biological systems with novel functionalities. Today, synthetic biology devices are making …

Resistance to antibiotics is an escalating global crisis, presenting a major health, social, and
economic burden. An underexplored alternative to antibiotic treatment is phage therapy …

Since the intimate relationship between microbes and human health has been uncovered,
microbes have been in the spotlight as therapeutic targets for several diseases. Microbes …

Bacteria sense and respond to the environment, communicate, and continuously interact
with their surroundings, including host bodies. For more than a century, engineers have …

Bacteria are emerging as living drugs to treat a broad range of disease indications.
However, the inherent advantages of these replicating and immunostimulatory therapies …

Naturally occurring microorganisms have been used therapeutically for over a century, but
the advent of modern techniques for genetic manipulation has created unprecedented …