Antibacterial peptides isolated from insects

L Otvos, Jr - Journal of peptide science: an official publication …, 2000 - Wiley Online Library
Insects are amazingly resistant to bacterial infections. To combat pathogens, insects rely on
cellular and humoral mechanisms, innate immunity being dominant in the latter category …

The inducible antibacterial peptides of insects

S Cociancich, P Bulet, C Hetru, JA Hoffmann - Parasitology today, 1994 - Elsevier
Insects respond to bacterial challenge by the rapid and transient synthesis of a large number
of potent antibacterial peptides that are active against many different bacteria. Two families …

Antimicrobial peptides in insects; structure and function

P Bulet, C Hetru, JL Dimarcq, D Hoffmann - Developmental & Comparative …, 1999 - Elsevier
Antimicrobial peptides appear to be ubiquitous and multipotent components of the innate
immune defense arsenal used by both prokaryotic and eukaryotic organisms. During the …

Insect defensins: inducible antibacterial peptides

JA Hoffmann, C Hetru - Immunology today, 1992 - cell.com
In response to bacterial challenge or trauma, insects produce a battery of bactericidal or
bacteriostatic molecules with a broad spectrum of activity against Gram-positive and~ or …

Insect Immunity: isolation from the lepidopteran heliothis virescensof a novel insect defensin with potent antifungal activity

M Lamberty, S Ades, S Uttenweiler-Joseph… - Journal of Biological …, 1999 - ASBMB
Lepidoptera have been reported to produce several antibacterial peptides in response to
septic injury. However, in marked contrast to other insect groups, no inducible antifungal …

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus

S Cociancich, A Dupont, G Hegy, R Lanot… - Biochemical …, 1994 - portlandpress.com
Insects belonging to the recent orders of the endopterygote clade (Lepidoptera, Diptera,
Hymenoptera and Coleoptera) respond to bacterial challenge by the rapid and transient …

Insect peptides with improved protease-resistance protect mice against bacterial infection

L Otvos, K Bokonyi, I Varga, BI Otvos, R Hoffmann… - Protein …, 2000 - cambridge.org
At a time of the emergence of drug-resistant bacterial strains, the development of
antimicrobial compounds with novel mechanisms of action is of considerable interest …

The medical potential of antimicrobial peptides from insects

M Tonk, A Vilcinskas - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
Antimicrobial peptides (AMPs) are peptide-based effector molecules produced by the innate
immune system to combat microbes. Insects produce the broadest repertoire of AMPs, and …

Peptide antimicrobial agents

H Jenssen, P Hamill, REW Hancock - Clinical microbiology …, 2006 - Am Soc Microbiol
Antimicrobial host defense peptides are produced by all complex organisms as well as
some microbes and have diverse and complex antimicrobial activities. Collectively these …

Antimicrobial peptides from animals: focus on invertebrates

J Vizioli, M Salzet - Trends in pharmacological sciences, 2002 - cell.com
An expensive group of cationic antimicrobial peptides has been isolated from animals and
plants during the past two decades. Three novel classes of natural antibiotics (anionic …