Relevance of astrocytic activation to reductions of astrocytic GABAA receptors

N Tateishi, T Shimoda, J Manako, S Katsumata… - Brain research, 2006 - Elsevier
Although astrocytes express γ-aminobutyric acid subtype-A (GABAA) receptors in the mature
brain, GABAA receptor expression in a cultivation state remains controversial. In this study …

Astrocytes as GABA-ergic and GABA-ceptive cells

BE Yoon, J Woo, C Justin Lee - Neurochemical research, 2012 - Springer
GABA (gamma-aminobutyric acid) is considered to be the major inhibitory neurotransmitter
that is synthesized in and released from GABA-ergic neurons in the brain. However, recent …

Astroglial Cells Express Large Amounts of GABAA Receptor Proteins in Mature Brain

M Bureau, J Laschet, M Bureau‐Heeren… - Journal of …, 1995 - Wiley Online Library
GABAA receptors were characterized in cellular fractions isolated from adult bovine brain.
The fraction enriched in cortical astrocytes is very rich in high‐affinity binding sites for [3H] …

GABA release from astrocytes in health and disease

W Kilb, S Kirischuk - International Journal of Molecular Sciences, 2022 - mdpi.com
Astrocytes are the most abundant glial cells in the central nervous system (CNS) mediating a
variety of homeostatic functions, such as spatial K+ buffering or neurotransmitter reuptake. In …

Astrocytic GABA receptors

DD Fraser, LA Mudrick‐Donnon, BA Macvicar - Glia, 1994 - Wiley Online Library
GABA receptors are distributed widely throughout the central nervous system on a variety of
cell types. It has become increasingly clear that astrocytes, both in cell culture and tissue …

GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes

DD Fraser, S Duffy, KJ Angelides… - Journal of …, 1995 - Soc Neuroscience
The properties of GABA receptor-mediated responses were examined in noncultured
astrocytes, acutely isolated from the mature rat hippocampus. Whole-cell patch clamping …

Functional expression of metabotropic GABAB receptors in primary cultures of astrocytes from rat cerebral cortex

M Oka, M Wada, Q Wu, A Yamamoto, T Fujita - … and biophysical research …, 2006 - Elsevier
GABAB receptor subunits are widely expressed on neurons throughout the central nervous
system (CNS), at both pre-and postsynaptic sites, where they mediate the late and slow …

Developmental profile and mechanisms of GABA‐induced calcium signaling in hippocampal astrocytes

SD Meier, KW Kafitz, CR Rose - Glia, 2008 - Wiley Online Library
GABA (γ‐aminobutyric acid) is a transmitter with dual action. Whereas it excites neurons
during the first week of postnatal development, it represents the major inhibitory transmitter …

GABA induces Ca2+ transients in astrocytes

M Nilsson, PS Eriksson, L Rönnbäck, E Hansson - Neuroscience, 1993 - Elsevier
By using the Ca 2+-sensitive indictor Fura-2/AM, the cytosolic Ca 2+ levels [Ca 2+] i were
measured in type 1 astrocytes in rat cortical astroglial primary cultures, after stimulation with …

Expression and Developmental Regulation of a GABAA Receptor in Cultured Murine Cells of the Oligodendrocyte Lineage

G Von Blankenfeld, J Trotter… - European Journal of …, 1991 - Wiley Online Library
The inhibitory neurotransmitter GABA activated Cl− currents in oligodendrocytes and their
precursor cells. Most of the pharmacological features of these GABA‐evoked currents …