Trypanosoma cruzi Infections l thank Dr Kierszenbaum for highlighting the complexities of
the participation of CD8* T cells in immunity and patho-genesis in Trypanosoma cruzi …

Infection of humans with the protozoan Trypanosoma cruzi leads to Chagas disease, or
American trypanosomiasis, a disease that affects nearly 20 million people, and constitutes …

The role of CD8+ T cells in immune control of Trypanosoma cruzi infection in mice was
examined by using in vivo depletion of CD8+ T cells with antibodies. Both the resistant …

In this paper, the infectivity for mice of Trypanosoma cruzi I and II strains isolated from
sylvatic animals, triatomines, and humans is determined using fresh blood examination …

The reproducibility of infection of C3H/He mice with T. cruzi clones Sylvio-X10/4 and Sylvio-
X10/7 maintained in the laboratory for 946 and 496 days respectively was assayed. Clone …

Mice infected with 5× 10 3 forms of Trypanosoma cruzi showed a transient, but severe
impairment of in vitro spleen cell responses to parasite antigens and to Concanavalin A …

The life cycle of the protozoan parasite Trypanosoma cruzi in mammalian hosts includes
both non‐dividing trypomastigote forms which circulate in the blood and replicating …

Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is
a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as …

Several studies in mice have strengthened the active role played either by CD4+, CD8+ or
both T cell subsets in conferring resistance of Trypanosoma cruzi infection. To date, no …

Mice injected with monoclonal antibody to the L3T4+ (CD4+) cell membrane surface
glycoprotein of T lymphocytes and immunized with antigens of Trypanosoma cruzi had …