The relationship between SARS-CoV-2 viral load and infectiousness is poorly known. Using
data from a cohort of cases and high-risk contacts, we reconstructed viral load at the time of …

Background Factors that lead to successful SARS-CoV-2 transmission are still not well
described. We investigated the association between a case's viral load and the risk of …

SARS-CoV-2 is difficult to contain because many transmissions occur during pre-
symptomatic infection. Unlike influenza, most SARS-CoV-2-infected people do not transmit …

Background: Understanding changes in infectiousness during SARS-COV-2 infections is
critical to assess the effectiveness of public health measures such as contact tracing …

The within-host viral kinetics of SARS-CoV-2 infection and how they relate to a person's
infectiousness are not well understood. This limits our ability to quantify the impact of …

SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …

INTRODUCTION Several novel variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …

A relationship between the infecting dose and the risk of disease severity has not been
demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that …

Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiology of
coronavirus disease 2019 (COVID-19), is readily transmitted person to person. Optimal …

Understanding the risk of infection from household-and community-exposures and the
transmissibility of asymptomatic infections is critical to SARS-CoV-2 control. Limited previous …