Animal research suggests that the consolidation of fear and extinction memories depends
on N-methyl D-aspartate (NMDA)-type glutamate receptors. Using a fear conditioning and …

NMDA receptors are important for the acquisition, reconsolidation, and extinction of
memories. NMDA receptor antagonists impair these memory processes, whereas the partial …

NMDA receptor antagonists block conditioned fear extinction when injected systemically and
also when infused directly into the amygdala. Here we evaluate the ability of d-cycloserine …

Extinction of conditioned fear to a tone paired with foot shock is thought to involve the
formation of new memory. In support of this, previous studies have shown that extinction of …

Mechanisms of N-methyl-d-aspartate receptor-dependent synaptic plasticity contribute to the
acquisition and retention of conditioned fear memory. However, synaptic rules which may …

Infusions into the amygdala (a brain area essential for excitatory fear conditioning) of either
NMDA receptor antagonists or inhibitors of the NMDA receptor‐linked mitogen activated …

Evidence suggests that extinction, the suppression of a learned response to a Pavlovian
signal that is produced by exposure to the signal alone after conditioning, is a consequence …

A number of studies have reported that d-cycloserine (DCS), a partial agonist of the N-
methyl-d-aspartate glutamate receptor, can facilitate the loss of conditioned fear if it is …

Activation of the N-methyl-d-aspartate receptor (NMDAR) glycine site has been shown to
enhance memory extinction in physiological and pathological conditions. In the current …

In anxiety disorders, such as posttraumatic stress disorders and phobias, classical
conditioning pairs natural (unconditioned) fear-eliciting stimuli with contextual or discrete …