Periodontal microorganisms not only colonize subgingival pockets, but also are detected on
various mucous membranes in patients with periodontitis. The object of this pilot study was …

Introduction: Periodontal diseases are the pathological manifestation of the host response
against the bacterial challenge from the dental biofilm at the tooth/gingival interface. The …

Inflammation is a driven force in modulating microbial communities, but little is known on the
interplay between colonizing microorganisms and the immune response in periodontitis …

Within the periodontium, the characteristic shift in microbial compositions that occurs during
the transition from health to disease has been well documented (132, 206). Concurrently, it …

In the mid-1960s the microbial aetiology of periodontal diseases was introduced based on
classical experimental gingivitis studies. Since then, numerous studies have addressed the …

The periodontium is a unique organ which consists of two soft connective tissues (gingiva
and periodontal ligament) and two calcified components (cementum and alveolar bone) …

The purpose of this volume of PERIODONTOLOGY 2000 is to present the basic concepts
and facts constituting the current understanding of the pathogenesis of human periodontitis …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Systemic conditions and disorders are now considered to be secondary factors modulating
disease initiation or progression rather than acting as primary etiological factors. The current …

The hypoxic microenvironment caused by oral pathogens is the most important cause of the
disruption of dynamic hemostasis between the oral microbiome and the immune system …