SARS-CoV-2: From structure to pathology, host immune response and therapeutic management

G Mihaescu, MC Chifiriuc, C Iliescu, CO Vrancianu… - Microorganisms, 2020 - mdpi.com
Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting
both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the …

Recent advances in pathophysiology, drug development and future perspectives of SARS-CoV-2

DD Singh, I Han, EH Choi, DK Yadav - Frontiers in cell and …, 2020 - frontiersin.org
The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic
disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensin-converting …

SARS-CoV-2: pathogenesis, therapeutics, variants, and vaccines

X Li, Z Mi, Z Liu, P Rong - Frontiers in Microbiology, 2024 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), emerged in December 2019 with staggering economic fallout …

COVID-19 pandemic: A multidisciplinary perspective on the pathogenesis of a novel coronavirus from infection, immunity and pathological responses

J Yi, J Miao, Q Zuo, F Owusu, Q Dong, P Lin… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus2 (SARS-CoV-2), has spread to more than 200 countries and regions, having a …

Molecular characterization of SARS-CoV-2

M Dermaku-Sopjani, M Sopjani - Current Molecular Medicine, 2021 - ingentaconnect.com
The coronavirus disease 2019 (COVID-19) is currently a new public health crisis threatening
the world. This pandemic disease is caused by severe acute respiratory syndrome …

Origin, pathogenesis, diagnosis and treatment options for SARS-CoV-2: a review

H Sajjad, M Majeed, S Imtiaz, M Siddiqah, A Sajjad… - Biologia, 2021 - Springer
Emerging viral infections are among the greatest challenges in the public health sector in
the twenty-first century. Among these, most of the viruses jump from other species of animals …

SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic

AA Rabaan, SH Al-Ahmed, R Sah, R Tiwari… - Annals of Clinical …, 2020 - Springer
A novel coronavirus (SARS-CoV-2), causing an emerging coronavirus disease (COVID-19),
first detected in Wuhan City, Hubei Province, China, which has taken a catastrophic turn with …

SARS-CoV-2: Current trends in emerging variants, pathogenesis, immune responses, potential therapeutic, and vaccine development strategies

A Salimi-Jeda, S Abbassi, A Mousavizadeh… - International …, 2021 - Elsevier
More than a year after the SARS-CoV-2 pandemic, the Coronavirus disease 19 (COVID-19)
is still a major global challenge for scientists to understand the different dimensions of …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

[HTML][HTML] Distinct molecular mechanisms characterizing pathogenesis of SARS-CoV-2

SJ Lee, YJ Kim, DG Ahn - Journal of Microbiology and …, 2022 - ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
continued for over 2 years, following the outbreak of coronavirus-19 (COVID-19) in 2019. It …