Publisher Summary Renal disease ranks as the foremost cause of morbidity and mortality in
systemic lupus erythematosus (SLE). Although several different end organs can be targeted …

Lupus nephritis (LN) is a major cause of morbidity and mortality in systemic lupus
erythematosus (SLE). The mechanisms of renal damage are complex. LN is characterized …

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown cause that can
occur at almost any age, although it affects mostly women in their 20s. The annual incidence …

Lupus nephritis is a serious potential feature of systemic lupus erythematous (SLE). Though
SLE typically cycles through periods of flares and remission, patients often eventually …

Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterized by a
striking female predominance and frequent development of glomerulonephritis. Renal …

Nephritis was first recognized as a component of systemic lupus erythematosus (SLE) by Sir
William Osler. Long considered rare, it was not until the 1940s that the prevalence and …

Lupus nephritis contributes notably to the morbidity and mortality of systemic lupus
erythematosus. Improved medical therapies have increased the median survival of patients …

Immune-mediated nephritis is a common complication of systemic lupus erythematosus
(SLE). It is now clear that multiple and independent mechanisms contribute to disease onset …

The kidney is the most commonly involved major internal organ in patients with systemic
lupus erythematosus (SLE). It is important to recognize that lupus kidney disease is not …

Severe inflammation of the kidney can indicate the serious, negative prognosis of lupus
nephritis when present in conjunction with systemic lupus erythematosus (SLE), a chronic …