Background. Ischemia-reperfusion injury is a major cause of early graft dysfunction after liver
transplantation. Tauroursodeoxycholic acid (TUDCA), a natural amidated hydrophilic bile …

In an attempt to decrease toxicity in high-risk patients undergoing unrelated donor
hematopoietic stem cell transplantation (URD HSCT), we tested a combination of …

Background: We have investigated a novel nonmyeloablative conditioning regimen in 44
patients with hematological malignancies. The median patient age was 41 years. Many of …

Because of its potent immunosuppressive yet stem cell–sparing activity, high-dose
cyclophosphamide was tested as sole prophylaxis of graft-versus-host disease (GVHD) after …

OBJECTIVE: When ursodeoxycholic acid (UDCA) is used for the treatment of primary biliary
cirrhosis, it has been associated with biochemical improvement, histological stability …

Despite near universal use of ursodeoxycholic acid (UDCA) several patients with PBC still
progress to liver transplant (LT) or death. Pruritus and fatigue are the most common …

The utility of GVHD prophylaxis with cyclosporin, MTX and prednisolone (CSA/MTX/Pred) in
allogeneic PBPC transplants is not well described although there are published data using …

Ursodeoxycholic acid (UDCA) makes up a small portion of the naturally occurring bile acid
pool in humans, and the drug is effective in several diseases. The mechanism of action …

OBJECTIVE: The principal objective of this study was to determine whether a relationship
exists between trough cyclosporine concentrations measured by HPLC and the …

Background: Ursodeoxycholic acid (UDCA) has been shown to improve serum levels of liver
enzymes and bilirubin in primary biliary cirrhosis (PBC). However, it is still uncertain whether …