Low incidence of acute graft-versus-host disease and recurrent leukaemia in patients undergoing allogeneic haemopoietic stem cell transplantation from sibling …

JL Byrne, C Stainer, H Hyde, G Miflin… - Bone marrow …, 1998 - nature.com
One of the major aims of allogeneic haemopoietic stem cell transplantation has been the
effective suppression of graft-versus-host disease (GVHD) without loss of a graft-versus …

[HTML][HTML] Improving safety and outcomes after allogeneic hematopoietic cell transplantation: a single-center experience

MQ Salas, I Pasic, M Remberger… - … and Cellular Therapy, 2022 - Elsevier
The implementation of dual T-cell depletion comprising 4.5 mg/kg of antithymocyte globulin
(ATG), post-transplantation cyclophosphamide, and cyclosporine A for reduced-intensity …

Ursodeoxycholic acid in the treatment of primary biliary cirrhosis: a short‐term, randomized, double‐blind controlled, cross‐over study with long‐term follow up

SJ HWANG, CY CHAN, SD LEE, JC WU… - Journal of …, 1993 - Wiley Online Library
In order to evaluate the efficacy of ursodeoxycholic acid (UDCA) in the treatment of Chinese
patients with primary biliary cirrhosis, a short‐term, randomized, double‐blind controlled …

Low molecular weight heparin for the prevention of hepatic veno-occlusive disease (VOD) after hematopoietic stem cell transplantation: a prospective phase II study

DL Forrest, K Thompson, VG Dorcas… - Bone marrow …, 2003 - nature.com
We evaluated 40 patients undergoing high-dose chemo/radiotherapy (HDCT) and
hematopoietic stem cell transplantation (HSCT)(allogeneic (22), autologous (18)) to …

Controlled, randomized, open-label trial of risk-stratified corticosteroid prevention of acute graft-versus-host disease after haploidentical transplantation

YJ Chang, LP Xu, Y Wang, XH Zhang… - Journal of Clinical …, 2016 - ascopubs.org
Purpose This study evaluated whether a prophylaxis strategy directed by the graft-versus-
host disease (GVHD) biomarker might reduce the 100-day incidence of acute GVHD grades …

Prophylaxis and treatment of GVHD after allogeneic haematopoietic SCT: a survey of centre strategies by the European Group for Blood and Marrow Transplantation

T Ruutu, A Van Biezen, B Hertenstein… - Bone marrow …, 2012 - nature.com
Recommendations on indications for allogeneic haematopoietic SCT have been presented,
but transplantation techniques remain poorly standardized. Pre-transplant risk factors are …

[HTML][HTML] Post-transplant cyclophosphamide versus anti-thymocyte globulin as graft-versus-host disease prophylaxis in haploidentical transplant

A Ruggeri, Y Sun, M Labopin, A Bacigalupo… - …, 2017 - ncbi.nlm.nih.gov
Severe graft-versus-host disease is a major barrier for non-T-cell-depleted haploidentical
stem cell transplantation. There is no consensus on the optimal graft-versus-host disease …

Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT

SW Choi, T Braun, I Henig, E Gatza… - Blood, The Journal …, 2017 - ashpublications.org
The oral histone deacetylase (HDAC) inhibitor (vorinostat) is safe and results in low
incidence of acute graft-versus-host disease (GVHD) after reduced-intensity conditioning …

A phase 3 double-blind study of the addition of tocilizumab vs placebo to cyclosporin/methotrexate GVHD prophylaxis

GA Kennedy, SK Tey, L Buizen… - Blood, The Journal …, 2021 - ashpublications.org
We determined the efficacy of tocilizumab (TCZ) in preventing grade 2-4 acute graft-versus-
host disease (aGVHD) in patients with acute leukemia or myelodysplasia undergoing …

[HTML][HTML] Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with …

W Sabry, R Le Blanc, AC Labbé, G Sauvageau… - Biology of Blood and …, 2009 - Elsevier
Incidence of grade II-IV acute graft-versus-host disease (aGVHD) in nonmyeloablative
(NMA) transplant recipients remains high. To date, the ideal prophylaxis regimen, which …