[HTML][HTML] Metabolomics approaches in pancreatic adenocarcinoma: tumor metabolism profiling predicts clinical outcome of patients

S Battini, F Faitot, A Imperiale, AE Cicek, C Heimburger… - BMC medicine, 2017 - Springer
Abstract Background Pancreatic adenocarcinomas (PAs) have very poor prognoses even
when surgery is possible. Currently, there are no tissular biomarkers to predict long-term …

Metabolic tumor burden: a new promising way to reach precise personalized therapy in PDAC

J Xiang, L Liu, W Wang, H Xu, C Wu, J Xu, C Liu… - Cancer letters, 2015 - Elsevier
Pancreatic cancer is currently one of the deadliest solid malignancies and pancreatic ductal
adenocarcinoma (PDAC) is the most common type of pancreatic cancer. In the past decade …

[HTML][HTML] Discovery of pancreatic adenocarcinoma biomarkers by untargeted metabolomics

A Martín-Blázquez, C Jiménez-Luna, C Díaz… - Cancers, 2020 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal
cancers, with a 5-year survival rate of less than 5%. In fact, complete surgical resection …

[HTML][HTML] Plasma metabolomics predicts chemotherapy response in advanced pancreatic cancer

H Muranaka, A Hendifar, A Osipov, N Moshayedi… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a clinically heterogeneous disease, and treatment
leads to different outcomes for people with similar diagnoses. Identifying patients who may …

[HTML][HTML] Metabolomic biomarkers of pancreatic cancer: a meta-analysis study

KY Mehta, HJ Wu, SS Menon, Y Fallah, X Zhong… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is
no blood test for early detection and diagnosis of this disease. Several research groups …

The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma

HB Moore, R Culp-Hill, JA Reisz, PJ Lawson… - The American Journal of …, 2019 - Elsevier
Background A reliable biomarker to detect pancreatic ductal adenocarcinoma (PDAC)
continues to be elusive. With employing metabolomics we hypothesize that a broader …

Biomarkers for pancreatic cancer based on tissue and serum metabolomics analysis in a multicenter study

R Zhao, S Ren, C Li, K Guo, Z Lu, L Tian, J He… - Cancer …, 2023 - Wiley Online Library
Background Early detection of pancreatic ductal adenocarcinoma (PDAC) may improve the
prognosis of patients. This study was to identify metabolic features of PDAC and to discover …

Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes

P Guo, T Teng, W Liu, Y Fang, B Wei… - … Journal of Cancer, 2022 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is characterized by high heterogeneity, and the
postoperative prognosis of different patients often varies greatly. Therefore, the classification …

[HTML][HTML] Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites

IM Di Gangi, T Mazza, A Fontana, M Copetti, C Fusilli… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Purpose pancreatic adenocarcinoma is the fourth leading cause of cancer related deaths
due to its aggressive behavior and poor clinical outcome. There is a considerable variability …

Pancreatic ductal adenocarcinoma is associated with a distinct urinary metabolomic signature

VW Davis, DE Schiller, D Eurich, OF Bathe… - Annals of surgical …, 2013 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with
poor prognosis in part due to the lack of early detection and screening methods …