Is a high HDL-cholesterol level always beneficial?

B Franczyk, J Rysz, J Ławiński, M Rysz-Górzyńska… - Biomedicines, 2021 - mdpi.com
The specific interest concerning HDL cholesterol (HDL-C) is related to its ability to uptake
and return surplus cholesterol from peripheral tissues back to the liver and, therefore, to its …

HDL cholesterol: reappraisal of its clinical relevance

W März, ME Kleber, H Scharnagl, T Speer… - Clinical Research in …, 2017 - Springer
Background While several lines of evidence prove that elevated concentrations of low-
density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its …

HDL‐c is a powerful lipid predictor of cardiovascular diseases

E Bruckert, B Hansel - International journal of clinical practice, 2007 - Wiley Online Library
Relationship between HDL‐c and cardiovascular diseases: Beyond the role of low‐density
lipoprotein cholesterol (LDL‐c) in the development of atherosclerosis, growing evidence …

Metabolism of HDL and its regulation

D Kardassis, I Mosialou, M Kanaki… - Current medicinal …, 2014 - ingentaconnect.com
Epidemiological studies have shown that low plasma levels of High Density Lipoprotein
Cholesterol (HDL-C) are associated with an increased risk for myocardial infarction. These …

HDL biogenesis and functions: role of HDL quality and quantity in atherosclerosis

EM Tsompanidi, MS Brinkmeier, EH Fotiadou… - Atherosclerosis, 2010 - Elsevier
Coronary heart disease (CHD) is a leading cause of death in western societies. In the last
few decades, a number of epidemiological studies have shown that a disproportion between …

Biological consequences of dysfunctional HDL

A Pirillo, AL Catapano… - Current medicinal …, 2019 - ingentaconnect.com
Epidemiological studies have suggested an inverse correlation between high-density
lipoprotein (HDL) cholesterol levels and the risk of cardiovascular disease. HDLs promote …

HDL: Quality or quantity?

CG Santos-Gallego - Atherosclerosis, 2015 - atherosclerosis-journal.com
In the last six decades, high density lipoproteins (HDL) have been extensively considered to
reduce the risk for coronary artery disease (CAD); in fact, the cholesterol carried by HDL …

HDL: the metabolism, function, and therapeutic importance

M Wang, MR Briggs - Chemical reviews, 2004 - ACS Publications
Epidemiological studies point to an inverse relationship between high-density lipoprotein
(HDL) levels and the risk of coronary artery disease (CAD). 1-5 Clinical trials such as the …

HDL and cardiovascular risk: time to call the plumber?

B Hewing, KJ Moore, EA Fisher - Circulation research, 2012 - Am Heart Assoc
High-density lipoprotein cholesterol (HDL-C) has been dubbed the good cholesterol
because it is thought to reflect the ability of HDL particles to remove excess cholesterol …

The changing face of HDL and the best way to measure it

SK Karathanasis, LA Freeman, SM Gordon… - Clinical …, 2017 - academic.oup.com
Abstract BACKGROUND HDL cholesterol (HDL-C) is a commonly used lipid biomarker for
assessing cardiovascular health. While a central focus has been placed on the role of HDL …