Quantification of small molecules in plasma with direct analysis in real time tandem mass spectrometry, without sample preparation and liquid chromatographic …

Y Zhao, M Lam, D Wu, R Mak - … of Up‐to‐the‐Minute Research …, 2008 - Wiley Online Library
Recently, a new ion source, Direct Analysis in Real Time (DART), has been introduced
which allows direct biological sample introduction into a mass spectrometry (MS) system …

[PDF][PDF] Direct analysis in real time (DART) mass spectrometry

RB Cody, JA Laramée, JM Nilles, HD Durst - JEOL news, 2005 - researchgate.net
Mass Spectrometry (MS) is one of the fastest-growing areas in analytical instrumentation.
The use of mass spectrometry in support of synthetic, organic, and pharmaceutical chemistry …

Determination of drugs and drug‐like compounds in different samples with direct analysis in real time mass spectrometry

ES Chernetsova, GE Morlock - Mass Spectrometry Reviews, 2011 - Wiley Online Library
Direct analysis in real time (DART), a relatively new ionization source for mass spectrometry,
ionizes small‐molecule components from different kinds of samples without any sample …

Direct analysis in real time—a critical review on DART-MS

JH Gross - Analytical and bioanalytical chemistry, 2014 - Springer
Direct analysis in real time mass spectrometry (DART-MS) has become an established
technique for rapid mass spectral analysis of a large variety of samples. DART-MS is …

Bioanalysis without sample cleanup or chromatography: the evaluation and initial implementation of direct analysis in real time ionization mass spectrometry for the …

S Yu, E Crawford, J Tice, B Musselman… - Analytical …, 2009 - ACS Publications
Two key bottlenecks in pharmaceutical bioanalysis are sample cleanup and
chromatographic separations. Although multiple approaches have been developed in the …

Direct analysis in real time–high resolution mass spectrometry as a valuable tool for the pharmaceutical drug development

J Srbek, B Klejdus, M Douša, J Břicháč, P Stasiak… - Talanta, 2014 - Elsevier
In this study, direct analysis in real time-mass spectrometry (DART-MS) was assessed for the
analysis of various pharmaceutical formulations with intention to summarize possible …

[HTML][HTML] Direct analysis in real time-mass spectrometry for rapid quantification of five anti-arrhythmic drugs in human serum: application to therapeutic drug monitoring

Y Gui, Y Lu, S Li, M Zhang, X Duan, CC Liu, J Jia… - Scientific reports, 2020 - nature.com
Therapeutic drug monitoring (TDM) is necessary for the optimal administration of anti-
arrhythmic drugs in the treatment of heart arrhythmia. The present study aimed to develop …

Applications of direct analysis in real time mass spectrometry in food analysis: A review

X Zhang, X Ren, K Chingin - Rapid Communications in Mass …, 2021 - Wiley Online Library
Rationale Direct analysis in real time (DART) combined with mass spectrometry (MS)
detection has become one of the most broadly used analytical approaches for the direct …

Direct analysis in real time mass spectrometry for the rapid identification of four highly hazardous pesticides in agrochemicals

L Wang, P Zhao, F Zhang, Y Li… - Rapid Communications in …, 2012 - Wiley Online Library
RATIONALE Direct analysis in real time (DART) is a new ion source technique, which is
conducted in the open air under ambient conditions, applied to the rapid and direct analysis …

[HTML][HTML] Direct analysis in real time mass spectrometry: a powerful tool for fast analysis

X Li, X Wang, L Li, Y Bai, H Liu - Mass Spectrometry Letters, 2015 - oak.go.kr
The appearance of ambient mass spectrometry (AMS) is undoubtedly a millstone in the field
of mass spectrometry. It allows for the direct analysis of ordinary objects in the open …