Introduction Two types of vaccines are currently licensed for use against pertussis: whole-
cell (wP) and acellular pertussis (aP). There is evidence that wP confers more durable …

Background. Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed
to have similar short-term (< 3 years after completion of the primary series) efficacy …

After the pertussis vaccine had been introduced in the 1940s and was shown to be very
successful in reducing the morbidity and mortality associated with the disease, the possibility …

Pertussis is a common respiratory infection caused by the bacterium Bordetella pertussis.
Although most cases occur in developing countries, it is considered endemic globally. The …

Pertussis is an acute respiratory disease caused by Bordetella pertussis. Due to its
frequency and severity, prevention of pertussis has been considered an important public …

Abstract Background In England, acellular pertussis (aP) vaccines replaced whole-cell
pertussis (wP) vaccine in the primary immunization course in October 2004. Despite …

A comprehensive review of observational pertussis vaccine effectiveness (VE) studies is
needed to update gaps from previous reviews. We conducted a systematic review of VE and …

Universal pertussis vaccination continues to prevent a previously common and serious
disease of childhood. Despite widespread gains in disease control, pertussis has not been …

Background. Unexpected waning of immunity after pertussis vaccination is now well
described. In this study we examined whether prior vaccination with whole-cell pertussis …

The common adverse reactions associated with diphtheria, tetanus and pertussis (DTP)
vaccination are less frequent and less severe with acellular DTP (DTaP) vaccines than with …