Analyzing host cells' transcriptional response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection will help delineate biological processes underlying …

SARS-CoV-2 induces a muted innate immune response compared to other respiratory
viruses. Mitochondrial dynamics might partially mediate this effect of SARS-CoV-2 on innate …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …

Viruses manipulate cellular metabolism and macromolecule recycling processes like
autophagy. Dysregulated metabolism might lead to excessive inflammatory and …

Mitochondria get caught in the crossfire of coronavirus disease 2019 (COVID-19) and
antiviral immunity. The mitochondria-mediated antiviral immunity represents the host's first …

Rationale Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-
19 pneumonia. We hypothesize that SARS-CoV-2 causes alveolar injury and hypoxemia by …

Mitochondria, which is essential for adequate innate immune response, energy metabolism
and mitochondria reactive oxygen species (ROS) production, might be in the cross fire of …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
diverse clinical manifestations and tissue injuries in multiple organs. However, cellular and …

The current pandemic of coronavirus disease 19 (COVID-19) has affected millions of
individuals and caused thousands of deaths worldwide. The pathophysiology of the disease …

Background The spread of a novel severe acute respiratory syndrome corona virus 2 (SARS-
CoV-2) has affected both the public health and the global economy. The current study was …