Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …

[HTML][HTML] Immune characteristics of severe and critical COVID-19 patients

L Yang, J Gou, J Gao, L Huang, Z Zhu, S Ji… - Signal transduction and …, 2020 - nature.com
Recently, the novel coronavirus disease (COVID-19) has broken out worldwide, 1 with rapid
increase of infected patients. COVID-19 dominantly leads to pneumonia. 2 Among these …

[HTML][HTML] Cellular immune response to COVID-19 and potential immune modulators

X Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a new member of the
coronavirus family that can cause coronavirus disease 2019 (COVID‐19). COVID‐9 has …

Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China

M Tan, Y Liu, R Zhou, X Deng, F Li, K Liang… - Immunology, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a respiratory disorder caused by the
highly contagious severe acute respiratory syndrome coronavirus 2. The …

[HTML][HTML] Immunosuppression as a hallmark of critical COVID-19: prospective study

E Kalicińska, D Szymczak, A Zińczuk, B Adamik… - Cells, 2021 - mdpi.com
The dysregulation of both the innate and adaptive responses to SARS-CoV-2 have an
impact on the course of COVID-19, and play a role in the clinical outcome of the disease …

Severe COVID-19: immunosuppression or hyperinflammation?

Y Liu, Y Li, D Xu, J Zhang, Z Peng - Shock, 2021 - journals.lww.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic has swept over the world and
causes thousands of deaths. Although the clinical features of COVID-19 become much …

[HTML][HTML] COVID-19 pandemic: A multidisciplinary perspective on the pathogenesis of a novel coronavirus from infection, immunity and pathological responses

J Yi, J Miao, Q Zuo, F Owusu, Q Dong, P Lin… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus2 (SARS-CoV-2), has spread to more than 200 countries and regions, having a …