Emerging role for NK cells in the pathogenesis of inflammatory arthropathies

P Conigliaro, R Scrivo, G Valesini, R Perricone - Autoimmunity reviews, 2011 - Elsevier
Natural killer (NK) cells are large, granular lymphocytes devoted to the defense against
microbial agents and cancer cells, traditionally recognized as an important arm of the innate …

The role of natural killer cells in autoimmune diseases

UC Kucuksezer, E Aktas Cetin, F Esen… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

NK cells in autoimmune diseases: Linking innate and adaptive immune responses

E Gianchecchi, DV Delfino, A Fierabracci - Autoimmunity Reviews, 2018 - Elsevier
The pathogenesis of autoimmunity remains to be fully elucidated, although the contribution
of genetic and environmental factors is generally recognized. Despite autoimmune …

NK cells in autoimmunity: a two-edg'd weapon of the immune system

R Perricone, C Perricone, C De Carolis… - Autoimmunity reviews, 2008 - Elsevier
Natural killer (NK) cells are part of the innate-immune system and respond rapidly to a
variety of insults via cytokine secretion and cytolytic activity. Their main function is first line of …

Natural killer cells in human autoimmune diseases

N Schleinitz, F Vély, JR Harlé, E Vivier - Immunology, 2010 - Wiley Online Library
Natural killer (NK) cells have been implicated in tumour surveillance and in the early control
of several microbial infections. In autoimmune disease their involvement in these processes …

The role of NK cells in rheumatoid arthritis

A Fathollahi, LN Samimi, M Akhlaghi, A Jamshidi… - Inflammation …, 2021 - Springer
Objective Natural killer (NK) cells are part of the innate immune system which not only
provides a primary response to pathogenic conditions but can also play an important …

NK cells in autoimmune diseases: protective or pathogenic?

M Liu, S Liang, C Zhang - Frontiers in Immunology, 2021 - frontiersin.org
Autoimmune diseases generally result from the loss of self-tolerance (ie, failure of the
immune system to distinguish self from non-self), and are characterized by autoantibody …

The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: major contributors or essential homeostatic modulators?

DJ Ahern, FM Brennan - Immunology letters, 2011 - Elsevier
Natural Killer (NK) cells are lymphocytes of the innate immune system, originally described
by their capacity to control tumour cells and eliminate virus-infected cells. However …

NK cells-Dr. Jekyll and Mr. Hyde in autoimmune rheumatic diseases

T Hojjatipour, S Aslani, S Salimifard, H Mikaeili… - International …, 2022 - Elsevier
Natural killer (NK) cells belong to innate immune system that are large granular lymphocytes
differentiating from the common lymphoid progenitors. These cells were first identified by …

NK cells: elusive players in autoimmunity

S Johansson, L Berg, H Hall, P Höglund - Trends in immunology, 2005 - cell.com
Natural killer (NK) cells were once regarded as relatively simple cells of the innate immune
system. However, they are now revealing themselves as multifunctional regulatory cells that …