Dapk1 improves inflammation, oxidative stress and autophagy in LPS-induced acute lung injury via p38MAPK/NF-κB signaling pathway

T Li, YN Wu, H Wang, JY Ma, SS Zhai, J Duan - Molecular immunology, 2020 - Elsevier
Objective To investigate the impact of death-associated protein kinase 1 (Dapk1) on
lipopolysaccharide (LPS)-induced acute lung injury (ALI) via p38MAPK/NF-κB pathway …

[HTML][HTML] Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination

X Liu, H Cao, J Li, B Wang, P Zhang… - Cell Death & …, 2017 - nature.com
Lung ischemia-reperfusion (I/R) injury remains one of the most common complications after
various cardiopulmonary surgeries. The inflammation response triggered by the released …

Protective effects of polydatin on lipopolysaccharide-induced acute lung injury through TLR4-MyD88-NF-κB pathway

Q Jiang, M Yi, Q Guo, C Wang, H Wang, S Meng… - International …, 2015 - Elsevier
The purpose of this study was to investigate the protective effect of PD against
lipopolysaccharide (LPS)-induced acute lung injury (ALI) and explore its potential …

Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats

H Zhang, J Sha, X Feng, X Hu, Y Chen, B Li… - International …, 2019 - Elsevier
Acute lung injury (ALI) is a serious complication of sepsis and an important cause of death in
intensive care. Studies have shown that DEX can inhibit inflammation. However, the anti …

Suppression of NLRP3 inflammasome by Platycodin D via the TLR4/MyD88/NF-κB pathway contributes to attenuation of lipopolysaccharide induced acute lung injury …

Y Wu, D Huang, X Wang, C Pei, W Xiao, F Wang… - International …, 2021 - Elsevier
Acute lung injury (ALI) is a common clinical condition with a high mortality rate and no
specific treatment is available. An excessive inflammatory response contributes to the …

MitoQ alleviates LPS-mediated acute lung injury through regulating Nrf2/Drp1 pathway

L Hou, J Zhang, Y Liu, H Fang, L Liao, Z Wang… - Free Radical Biology …, 2021 - Elsevier
Lipopolysaccharide (LPS) has been known to cause alveolar epithelial cell (AEC) apoptosis
and barrier breakdown that characterize acute lung injury (ALI) and acute respiratory …

[HTML][HTML] PD-L1 maintains neutrophil extracellular traps release by inhibiting neutrophil autophagy in endotoxin-induced lung injury

C Zhu, J Xie, Z Zhao, P Li, Q Liu, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Programmed death ligand 1 (PD-L1) is not only an important molecule in mediating tumor
immune escape, but also regulates inflammation development. Here we showed that PD-L1 …

[HTML][HTML] Protective effects of dioscin against lipopolysaccharide-induced acute lung injury through inhibition of oxidative stress and inflammation

H Yao, Y Sun, S Song, Y Qi, X Tao, L Xu… - Frontiers in …, 2017 - frontiersin.org
The protective effects of dioscin, a natural steroidal saponin from some medicinal plants
including Dioscorea nipponica Makino, against lipopolysaccharide (LPS)-induced acute …

Anti-inflammatory effect of Yam Glycoprotein on lipopolysaccharide-induced acute lung injury via the NLRP3 and NF-κB/TLR4 signaling pathway

X Niu, L Zang, W Li, X Xiao, JJ Yu, Q Yao… - International …, 2020 - Elsevier
Acute lung injury (ALI) is a common lung disease accompanied by acute and persistent
pulmonary inflammatory response syndrome, which leads to alveolar epithelial cells and …

[HTML][HTML] Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury

H Amatullah, T Maron-Gutierrez, Y Shan, S Gupta… - Redox Biology, 2021 - Elsevier
Oxidative stress is considered one of the early underlying contributors of acute lung injury
(ALI) and ventilator-induced lung injury (VILI). DJ-1, also known as PARK7, has a well …