Growth differentiation factor 15 (GDF-15) levels associate with lower survival in chronic kidney disease patients with COVID-19

A Galassi, P Ciceri, V Bono, L Magagnoli, M Sala… - Biomedicines, 2022 - mdpi.com
A cytokine storm drives the pathogenesis of severe COVID-19 infection and several
biomarkers have been linked to mortality. Chronic kidney disease (CKD) emerged as a risk …

[PDF][PDF] High Plasma Levels of Fibroblast Growth Factor 23 Are Associated with Increased Risk of COVID-19 in End-Stage Renal Disease Patients on Hemodialysis …

L Toro, L Michea, A Parra-Lucares… - DOI: https://doi. org …, 2023 - academia.edu
End-stage renal disease (ESRD) patients are a population with high rates of COVID-19 and
mortality. These patients present a low response to anti-SARS-CoV-2 immunization, which is …

High plasma levels of fibroblast growth factor 23 are associated with increased risk of COVID-19 in end-stage renal disease patients on hemodialysis: results of a …

L Toro, L Michea, A Parra-Lucares, G Mendez-Valdes… - Toxins, 2023 - mdpi.com
End-stage renal disease (ESRD) patients are a population with high rates of COVID-19 and
mortality. These patients present a low response to anti-SARS-CoV-2 immunization, which is …

Circulating GDF-15 in relation to the progression and prognosis of chronic kidney disease: a systematic review and dose-response meta-analysis

Z Zhou, H Liu, H Ju, H Chen, H Jin, M Sun - European Journal of Internal …, 2023 - Elsevier
Background Patients with chronic kidney disease (CKD) typically exhibit circulating growth
differentiation factor-15 (GDF-15) at high levels. This meta-analysis aimed to evaluate the …

Growth differentiation factor 15 provides prognostic information superior to established cardiovascular and inflammatory biomarkers in unselected patients …

PL Myhre, C Prebensen, H Strand, R Røysland… - Circulation, 2020 - Am Heart Assoc
Background: Growth differentiation factor 15 (GDF-15) is a strong prognostic marker in
sepsis and cardiovascular disease (CVD). The prognostic value of GDF-15 in coronavirus …

GDF-15 Levels and Other Laboratory Findings as Predictors of COVID-19 Severity and Mortality: A Pilot Study

L Švitek, D Lišnjić, B Grubišić, M Zlosa, E Schönberger… - Biomedicines, 2024 - mdpi.com
Growth differentiation factor 15 (GDF-15) is a stress-induced cytokine associated with acute
and chronic inflammatory states. This prospective observational study aimed to investigate …

[HTML][HTML] Evaluation of plasma biomarkers to predict major adverse kidney events in hospitalized patients with COVID-19

S Menez, SG Coca, DG Moledina, Y Wen… - American Journal of …, 2023 - Elsevier
Rationale & Objective Patients hospitalized with COVID-19 are at increased risk for major
adverse kidney events (MAKE). We sought to identify plasma biomarkers predictive of MAKE …

GDF-15 predicts in-hospital mortality of critically ill patients with acute kidney injury requiring continuous renal replacement therapy: a multicenter prospective study

JH Lim, Y Jeon, JS Ahn, S Kim, DK Kim, JP Lee… - Journal of Clinical …, 2021 - mdpi.com
Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine. This study
evaluated the association between GDF-15 and in-hospital mortality among patients with …

Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity

S Bu, L Royston, T Mabanga, CA Berini… - Frontiers in …, 2024 - frontiersin.org
Introduction Growth differentiation factor 15 (GDF-15) was originally described as a stress-
induced cytokine, and a biomarker of aging and cardiovascular diseases. We hypothesized …

The predictive markers of severity and mortality in hospitalized hemodialysis patients with COVID‐19 during Omicron epidemic

M Banshodani, H Kawanishi, T Hirai… - Therapeutic …, 2023 - Wiley Online Library
Introduction Predictive markers and prognosis remain unclear in hospitalized hemodialysis
(HD) patients with coronavirus disease 2019 (COVID‐19) during the Omicron epidemic …