Completion of clinical trials in light of COVID-19

TK Burki - The Lancet Respiratory Medicine, 2020 - thelancet.com
Over the past few months, more than 80 000 Americans with COVID-19 have been treated
with convalescent plasma, under an expanded access programme. The programme was …

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

M Llewelyn, E Barbon, G Bassett, L Bennett, A Bexley… - sussex.figshare.com
Background Many patients with COVID-19 have been treated with plasma containing anti-
SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent …

Convalescent plasma therapy in COVID-19 critically ill patients during advanced phases of clinical trials and their preliminary results.

F Anselmo de Oliveira, M Penteado Nucci… - Einstein …, 2021 - search.ebscohost.com
❚ ABSTRACT The objective of this study was to highlight the global scientific effort to fight
the SARS-CoV-2, addressing the preliminary results of passive immunization through …

Convalescent plasma therapy in COVID-19 patients: a non-randomized case-control study with concurrent control

P Cacilhas, E Caberlon, L Angoleri… - Brazilian Journal of …, 2022 - SciELO Brasil
Convalescent plasma therapy has shown controversial results in coronavirus disease-19
(COVID-19) patients. We performed a non-randomized case-control study with …

[PDF][PDF] Is convalescent plasma futile in COVID-19

FLT Hamilton, D Arnold, R Lilford… - A Bayesian re-analysis …, 2021 - pure-oai.bham.ac.uk
abstract Background: Randomized trials are generally performed from a frequentist
perspective, which can conflate absence of evidence with evidence of absence. The …

Premier Peer-Reviewed Journal: Thanks Dr. Hagan

JS Daniels - Missouri Medicine, 2021 - search.proquest.com
Abstract John S. Daniels, MD Retiring Internal Medicine Missouri Medicine Editorial Board
Member, St. Louis Use of Convalescent Plasma in the Management of COVID-19 The …

Convalescent Plasma in COVID-19: To what Degree should Clinicians Rely on Currently Available Data?

W Alhazzani, R Jaeschke - Saudi Journal of Medicine & Medical …, 2021 - journals.lww.com
In this issue of the Saudi Journal of Medicine and Medical Sciences, AlShehry et al. report
the interim findings of a phase II trial that describes the outcomes of 40 hospitalized adults …

[PDF][PDF] Efficacy and Safety of High-Titer Anti-SARS-CoV-2 (COVID 19) Convalescent Plasma for Hospitalized Patients with Infection due to COVID-19 to Decrease …

JM Sturek, S Heysell, LG Lum, T Thomas, C Sheppard… - cdn.clinicaltrials.gov
Background: There are currently no proven treatment options for Coronavirus Disease 2019
(COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) …

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - MedRxiv, 2021 - medrxiv.org
Background Treatment of COVID-19 patients with plasma containing anti-SARS-CoV-2
antibodies may have a beneficial effect on clinical outcomes. We aimed to evaluate the …

[HTML][HTML] SUPPORT-E Consortium:“Covid-19 convalescent plasma should be further investigated”

H Schrezenmeier, V de Angelis, S Bégué, L Cannata… - bioengineer.org
On December 7 th, WHO updated its living guideline on COVID-19 therapeutics, including
convalescent plasma (CCP). This led to their recommendation against the use of CCP for …