Background Cancer stem-like cells (CSCs) are a subpopulation of tumor cells responsible
for tumor initiation, metastasis, chemoresistance, and relapse. Recently, CSCs have been …

Uveal melanoma (UM) is the most common primary ocular tumor in the adult population.
Even though these primary tumors are successfully treated in 90% of cases, almost 50% of …

Ocular tumors are a family of rare neoplasms that develop in the eye. Depending on the type
of cancer, they mainly originate from cells localized within the retina, the uvea, or the …

Background Uveal melanoma (UM) is the most common primary intraocular malignancy with
a strong tendency to metastasize. The prognosis is poor once metastasis occurs. The …

Fibroblast growth factors (FGFs) play non-redundant autocrine/paracrine functions in various
human cancers. The Cancer Genome Atlas (TCGA) data mining indicates that high levels of …

Purpose Tumor stem cells have emerged as a crucial focus of investigation and a
therapeutic target in the context of cancer metastasis and drug resistance. They represent a …

Background Although there has been some progress in the treatment of primary uveal
melanoma (UVM), distant metastasis remains the leading cause of death in patients …

Background Uveal melanoma (UM) is a rare and deadly eye cancer with high metastatic
potential. Despite the predominance of malignant cells within the tumor microenvironment …

Background: Uveal melanoma (UVM) is a form of eye cancer with a poor prognosis,
particularly in metastatic patients. This study aimed to elucidate the cellular heterogeneity …

Conjunctival melanoma (CoM) is a potentially devastating tumor that can lead to distant
metastasis. Despite various therapeutic strategies for distant metastatic CoM, the clinical …