Unveiling COVID-19 secrets: Harnessing Cytokines as powerful biomarkers for diagnosis and predicting severity

B Wolszczak-Biedrzycka, J Dorf… - Journal of …, 2023 - Taylor & Francis
Introduction In coronavirus disease (COVID-19), inflammation takes center stage, with a
cascade of cytokines released, contributing to both inflammation and lung damage. The …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

The Role of Inflammatory Cytokines (Interleukin-1 and Interleukin-6) as a Potential Biomarker in the Different Stages of COVID-19 (Mild, Severe, and Critical)

M Ghofrani Nezhad, G Jami, O Kooshkaki… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokine storm refers to the overproduction of immune and inflammatory cells and their
proteins (cytokines)[interleukin (IL)-1 and IL-6] causing acute respiratory distress syndrome …

Early Cytokine Signatures of Hospitalized Mild and Severe COVID-19 Patients: A Prospective Observational Study

AA Alfadda, K Siddiqui, M Rafiullah… - Journal of …, 2023 - Taylor & Francis
Background The severe manifestation of coronavirus disease 2019 (COVID-19) is known to
be mediated by several cytokines and chemokines. The study aimed to compare the early …

Inflammatory Markers and Cytokines in Moderate and Critical Cases of COVID-19.

SH Chang, D Minn, SW Kim, YK Kim - Clinical Laboratory, 2021 - search.ebscohost.com
Background: Inflammatory responses have been suggested to be associated with
coronavirus disease 2019 (COVID-19). This study investigated the inflammatory markers …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Extensive Study on Hematological, Immunological, Inflammatory Markers, and Biochemical Profile to Identify the Risk Factors in COVID‐19 Patients

ET Ali, A Sajid Jabbar, HS Al Ali… - International Journal …, 2022 - Wiley Online Library
Background. Tissue damage caused by COVID‐19 could be detected by several clinical
indicators including hematological, immunological, biochemical, and inflammatory markers …

Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19

C Herr, S Mang, B Mozafari, K Guenther… - Journal of …, 2021 - Taylor & Francis
Background COVID-19 comprises several severity stages ranging from oligosymptomatic
disease to multi-organ failure and fatal outcomes. The mechanisms why COVID-19 is a mild …

A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

Cytokine signature associated with disease severity in COVID-19

J Guo, S Wang, H Xia, D Shi, Y Chen, S Zheng… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) broke out and then became a global epidemic at the
end of 2019. With the increasing number of deaths, early identification of disease severity …