The aim of the present study was to examine the roles of l-fucose and the
glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate …

Chondroitin sulfate proteoglycans (CSPGs) are complex biomolecules that are known to
facilitate patterning of axonal direction and cell migration during the early growth and …

Metabolic glycoengineering (MGE) refers to a technique where non‐natural
monosaccharide analogs are introduced into living biological systems. Once inside a cell …

Glycosaminoglycans are natural heteropolysaccharides that are present in every
mammalian tissue. They are composed of repeating disaccharide units that consist of either …

Carbohydrate-based materials offer exciting opportunities for drug delivery. They present
readily available, biocompatible components for the construction of macromolecular systems …

Neuroprosthetic devices that record and modulate neural activities have demonstrated
immense potential for bypassing or restoring lost neurological functions due to neural …

Glycosaminoglycans (GAGs) are widely explored in the biomedical market as functional
ingredients in pharmaceutical or nutraceutical preparations. This extensive application of …

The mammalian central nervous system is organized by a variety of cells, such as neurons
and glial cells, that are generated from a common progenitor, the neural stem cell (NSC) …

Importance of the field: Till now, the importance of carbohydrates has been underscored, if
compared with the two other major classes of biopolymers such as oligonucleotides and …

We report the generation of chondroitin sulfate (CS) glycomimetics with tunable chemical
and biological properties. Our approach greatly simplifies the synthesis of complex …