Neurons are a key component of the nervous system and differentiate from multipotent
neural stem cells (NSCs). Chromatin remodeling has a critical role in the differentiation …

Chromatin remodeling plays a critical role in gene regulation and impacts many biological
processes. However, little is known about the relationship between chromatin remodeling …

A key question in developmental biology is how cellular differentiation is controlled during
development. While transitions between trithorax-group (TrxG) and polycomb-group (PcG) …

The nervous system consists of several hundred neuronal subtypes and glial cells that show
specific gene expression and are generated from common ancestors, neural stem cells …

Early neurodevelopment requires cell fate commitment from pluripotent stem cells to
restricted neural lineages, which involves the epigenetic regulation of chromatin structure …

During embryonic brain development, neural progenitor/stem cells (NPCs) sequentially give
rise to different subtypes of neurons and glia via a highly orchestrated process. To …

Early neural fate commitment is a key process in neural development and establishment of
the central nervous system, and this process is tightly controlled by extrinsic signals, intrinsic …

During development of the central nervous system, a small pool of stem cells and
progenitors generate the vast neural diversity required for neural circuit formation and …

During central nervous system development, spatiotemporal gene expression programs
mediate specific lineage decisions to generate neuronal and glial cell types from neural …

During embryonic brain development, neurogenesis requires the orchestration of gene
expression to regulate neural stem cell (NSC) fate specification. Epigenetic regulation with …