This review makes a critical evaluation of 61 peer‐reviewed manuscripts that use a docking
step in a virtual screening (VS) protocol to predict SARS‐CoV‐2 M‐pro (M‐pro) inhibitors in …

Antiviral therapeutics to treat SARS‐CoV‐2 are needed to diminish the morbidity of the
ongoing COVID‐19 pandemic. A well‐precedented drug target is the main viral protease …

The global emergency caused by COVID-19 makes the discovery of drugs capable of
inhibiting SARS-CoV-2 a priority, to reduce the mortality and morbidity of this disease …

Since the outbreak of the COVID-19 pandemic in December 2019 and its rapid spread
worldwide, the scientific community has been under pressure to react and make progress in …

The unprecedented pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is threatening global health. SARS-CoV-2 has caused severe disease with …

Background and Aims Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
induced Novel Coronavirus Disease (COVID-19) has currently become pandemic …

With numerous infections and fatalities, COVID-19 has wreaked havoc around the globe.
The main protease (Mpro), which cleaves the polyprotein to form non-structural proteins …

Wuhan, China was the epicenter of the first zoonotic transmission of the severe acute
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) in December 2019 and it is the …

Compound repurposing is an important strategy for the identification of effective treatment
options against SARS-CoV-2 infection and COVID-19 disease. In this regard, SARS-CoV-2 …

The outbreak of a new coronavirus (SARS-CoV-2), which is responsible for the COVID-19
disease and is spreading rapidly around the world, urgently requires effective therapeutic …