Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network

MA Andrade, P Chacon, JJ Merelo… - … , Design and Selection, 1993 - academic.oup.com
An optimized self-organizing map algorithm has been used to obtain protein topological
(proteinotopic) maps. A neural network is able to arrange a set of proteins depending on …

SOMCD: method for evaluating protein secondary structure from UV circular dichroism spectra

P Unneberg, JJ Merelo, P Chacón… - … Structure, Function, and …, 2001 - Wiley Online Library
This article presents SOMCD, an improved method for the evaluation of protein secondary
structure from circular dichroism spectra, based on Kohonen's self‐organizing maps (SOM) …

Proteinotopic feature maps

JJ Merelo, MA Andrade, A Prieto, F Morán - Neurocomputing, 1994 - Elsevier
In this paper a system based on Kohonen's SOM (Self-Organizing Map) for protein
classification according to Circular Dichroism (CD) spectra is described. As a result, proteins …

Protein secondary structure from circular dichroism spectroscopy: Combining variable selection principle and cluster analysis with neural network, ridge regression …

N Sreerama, RW Woody - Journal of molecular biology, 1994 - Elsevier
Different approaches to improve the analysis of protein secondary structure from circular
dichroism spectra are compared. Grouping proteins based on the similarity of their circular …

Quantitative analysis of protein far UV circular dichroism spectra by neural networks

G Böhm, R Muhr, R Jaenicke - Protein Engineering, Design and …, 1992 - academic.oup.com
A new method based on neural network theory is presented to analyze and quantify the
information content of far UV circular dichroism spectra. Using a backpropagation network …

The optimization of protein secondary structure determination with infrared and circular dichroism spectra

KA Oberg, JM Ruysschaert… - European journal of …, 2004 - Wiley Online Library
We have used the circular dichroism and infrared spectra of a specially designed 50 protein
database [Oberg, KA, Ruysschaert, JM & Goormaghtigh, E.(2003) Protein Sci. 12, 2015 …

BeStSel: a web server for accurate protein secondary structure prediction and fold recognition from the circular dichroism spectra

A Micsonai, F Wien, É Bulyáki, J Kun… - Nucleic acids …, 2018 - academic.oup.com
Circular dichroism (CD) spectroscopy is a widely used method to study the protein
secondary structure. However, for decades, the general opinion was that the correct …

Combining evolutionary information and neural networks to predict protein secondary structure

B Rost, C Sander - Proteins: Structure, Function, and …, 1994 - Wiley Online Library
Using evolutionary information contained in multiple sequence alignments as input to neural
networks, secondary structure can be predicted at significantly increased accuracy. Here, we …

K2D2: estimation of protein secondary structure from circular dichroism spectra

C Perez-Iratxeta, MA Andrade-Navarro - BMC structural biology, 2008 - Springer
Background Circular dichroism spectroscopy is a widely used technique to analyze the
secondary structure of proteins in solution. Predictive methods use the circular dichroism …

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra

C Louis‐Jeune, MA Andrade‐Navarro… - Proteins: Structure …, 2012 - Wiley Online Library
Circular dichroism (CD) is a spectroscopic technique commonly used to investigate the
structure of proteins. Major secondary structure types, alpha‐helices and beta‐strands …