Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study
Background Antipsychotic drugs improve schizophrenia symptoms and reduce the
frequency of relapse, but treatment response is highly variable. Little is known about the …
frequency of relapse, but treatment response is highly variable. Little is known about the …
How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete
A common belief among statistical geneticists is that genomewide association studies
1(GWAS) rendered candidate gene studies 2 obsolete. It is also widely believed that nearly …
1(GWAS) rendered candidate gene studies 2 obsolete. It is also widely believed that nearly …
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …
cannabis, cannabinoids, and cannabis based medicines and human health, from …
Association of high-potency cannabis use with mental health and substance use in adolescence
LA Hines, TP Freeman, SH Gage, S Zammit… - JAMA …, 2020 - jamanetwork.com
Importance Cannabis use is consistently linked to poorer mental health outcomes, and there
is evidence that use of higher-potency cannabis increases these risks. To date, no studies …
is evidence that use of higher-potency cannabis increases these risks. To date, no studies …
[HTML][HTML] The global epidemiology and contribution of cannabis use and dependence to the global burden of disease: results from the GBD 2010 study
Aims Estimate the prevalence of cannabis dependence and its contribution to the global
burden of disease. Methods Systematic reviews of epidemiological data on cannabis …
burden of disease. Methods Systematic reviews of epidemiological data on cannabis …
Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study
BackgroundSmoking prevalence is higher amongst individuals with schizophrenia and
depression compared with the general population. Mendelian randomisation (MR) can …
depression compared with the general population. Mendelian randomisation (MR) can …
Effects of cannabis use on outcomes of psychotic disorders: systematic review
S Zammit, THM Moore, A Lingford-Hughes… - The British Journal of …, 2008 - cambridge.org
BackgroundIt is unclear if research findings support clinical opinion that cannabis use leads
to worse outcomes in people with psychosis, or whether this impression is confounded by …
to worse outcomes in people with psychosis, or whether this impression is confounded by …
[HTML][HTML] Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis
Background Approximately 188 million people use cannabis yearly worldwide, and it has
recently been legalised in 11 US states, Canada, and Uruguay for recreational use. The …
recently been legalised in 11 US states, Canada, and Uruguay for recreational use. The …