Ghrelin increases anxiety-like behavior and memory retention in rats

VP Carlini, ME Monzón, MM Varas… - Biochemical and …, 2002 - Elsevier
Ghrelin is a peptide found in the hypothalamus and stomach that stimulates food intake and
whose circulating concentrations are affected by nutritional state. Very little is known about …

Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin

VP Carlini, MM Varas, AB Cragnolini… - Biochemical and …, 2004 - Elsevier
Ghrelin is a peptide hormone produced and secreted from the stomach. Hypothalamic
injection of the peptide increases food intake but it is not known if the peptide affects other …

The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence

M Alvarez-Crespo, KP Skibicka, I Farkas, CS Molnár… - 2012 - journals.plos.org
Here, we sought to demonstrate that the orexigenic circulating hormone, ghrelin, is able to
exert neurobiological effects (including those linked to feeding control) at the level of the …

A role of ghrelin in neuroendocrine and behavioral responses to stress in mice

A Asakawa, A Inui, T Kaga, H Yuzuriha, T Nagata… - …, 2001 - karger.com
Ghrelin, an endogenous ligand of the growth hormone secretagogue receptor, was recently
identified in the rat stomach. Previous studies have shown that ghrelin potently increases …

Ghrelin is an orexigenic peptide and elicits anxiety-like behaviors following administration into discrete regions of the hypothalamus

PJ Currie, R Khelemsky, EM Rigsbee, LM Dono… - Behavioural brain …, 2012 - Elsevier
Previous evidence indicates that peripherally administered ghrelin significantly increases
corticotropin releasing hormone (CRH) mRNA and serum corticosterone. In addition …

Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake

VP Carlini, RC Gaydou, HB Schiöth, SR de Barioglio - Regulatory peptides, 2007 - Elsevier
Ghrelin (Ghr) is an appetite stimulating hormone that is produced peripherally, by the
stomach, and centrally as well. Previous investigations show that Ghr increases food intake …

The effects of ghrelin on sleep, appetite, and memory, and its possible role in depression: a review of the literature

V Morin, F Hozer, JF Costemale-Lacoste - L'encephale, 2018 - Elsevier
Objectives Ghrelin is an orexigenic digestive hormone that plays a role in sleep and
memory. Our work aims is to synthesize the effects of ghrelin on appetite, sleep and memory …

Ghrelin alleviates anxiety-and depression-like behaviors induced by chronic unpredictable mild stress in rodents

HJ Huang, XC Zhu, QQ Han, YL Wang, N Yue… - Behavioural Brain …, 2017 - Elsevier
As a regulator of food intake, ghrelin also plays a key role in mood disorders. Previous
studies reported that acute ghrelin administration defends against depressive symptoms of …

Anxiolytic-like effects of increased ghrelin receptor signaling in the amygdala

M Jensen, C Ratner, O Rudenko… - International Journal …, 2016 - academic.oup.com
Background: Besides the well-known effects of ghrelin on adiposity and food intake
regulation, the ghrelin system has been shown to regulate aspects of behavior including …

The extra-hypothalamic actions of ghrelin on neuronal function

ZB Andrews - Trends in neurosciences, 2011 - cell.com
Ghrelin is a peptide hormone produced and secreted in the stomach. Numerous studies
over the past decade demonstrate its importance in food intake, body-weight regulation and …