Diastolic dysfunction and heart failure with preserved ejection fraction: understanding mechanisms by using noninvasive methods

M Obokata, YNV Reddy, BA Borlaug - JACC: Cardiovascular Imaging, 2020 - jacc.org
Research in the last decade has substantially advanced our understanding of the
pathophysiology of heart failure with preserved ejection fraction (HFpEF). However …

Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment

BA Borlaug, WJ Paulus - European heart journal, 2011 - academic.oup.com
Half of patients with heart failure (HF) have a preserved left ventricular ejection fraction
(HFpEF). Morbidity and mortality in HFpEF are similar to values observed in patients with HF …

Heart failure with preserved ejection fraction: refocusing on diastole

A Abbate, R Arena, N Abouzaki, BW Van Tassell… - International journal of …, 2015 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome of exercise
intolerance and/or congestion, in the presence of a left ventricular (LV) ejection fraction …

Heart failure with preserved ejection fraction: insights into diagnosis and pathophysiology

SF Nagueh - Cardiovascular Research, 2021 - academic.oup.com
Heart failure with preserved ejection fraction (HFpEF) accounts for at least half the cases of
heart failure, currently diagnosed. There are several cardiac and non-cardiac manifestations …

Mechanisms, diagnosis, and treatment of heart failure with preserved ejection fraction and diastolic dysfunction

GD Plitt, JT Spring, MJ Moulton… - Expert review of …, 2018 - Taylor & Francis
Introduction: Heart failure with preserved ejection fraction (HFpEF) continues to be a major
challenge for clinicians. Many crucial aspects of the syndrome remain unclear, including the …

Heart failure with preserved ejection fraction: new approaches to diagnosis and management

B Upadhya, DW Kitzman - Clinical cardiology, 2020 - Wiley Online Library
The majority of older patients who develop heart failure (HF), particularly older women, have
a preserved left ventricular ejection fraction (HFpEF). Patients with HFpEF have severe …

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

Prognostic importance of pathophysiologic markers in patients with heart failure and preserved ejection fraction

MA Burke, DH Katz, L Beussink, S Selvaraj… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome associated with multiple pathophysiologic abnormalities, including left ventricular …

Diagnosis and management of heart failure with preserved ejection fraction: 10 key lessons

A Afsin Oktay, SJ Shah - Current cardiology reviews, 2015 - ingentaconnect.com
Heart failure with preserved ejection fraction (HFpEF) is a common clinical syndrome
associated with high rates of morbidity and mortality. Due to the lack of evidence-based …

Heart failure with normal left ventricular ejection fraction

MT Maeder, DM Kaye - Journal of the American College of Cardiology, 2009 - jacc.org
It is estimated that approximately 50% of the heart failure population has a normal left
ventricular ejection fraction, a complex broadly referred to as heart failure with normal left …