A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates

K Mallilankaraman, DJ Shedlock, H Bao… - PLoS neglected …, 2011 - journals.plos.org
Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus indigenous to
tropical Africa and Asia. Acute illness is characterized by fever, arthralgias, conjunctivitis …

Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus

K Muthumani, KM Lankaraman, DJ Laddy… - Vaccine, 2008 - Elsevier
Chikungunya virus (CHIKV) is an emerging arbovirus and is an important human pathogen.
Infection of humans by CHIKV can cause a syndrome characterized by fever, headache …

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice

D Hallengärd, M Kakoulidou, A Lulla… - Journal of …, 2014 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus that has caused
severe epidemics in Africa and Asia and occasionally in Europe. As of today, there is no …

DNA vaccine initiates replication of live attenuated chikungunya virus in vitro and elicits protective immune response in mice

I Tretyakova, J Hearn, E Wang… - The Journal of …, 2014 - academic.oup.com
Background. Chikungunya virus (CHIKV) causes outbreaks of chikungunya fever worldwide
and represents an emerging pandemic threat. Vaccine development against CHIKV has …

Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model

H Chu, SC Das, JF Fuchs, M Suresh, SC Weaver… - Vaccine, 2013 - Elsevier
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, recently re-emerged in Africa and
spread to islands in the Indian Ocean, the Indian subcontinent, and to South East Asia …

Prime-boost immunization strategies against Chikungunya virus

D Hallengärd, FM Lum, BM Kümmerer, A Lulla… - Journal of …, 2014 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus that causes
debilitating arthralgia in humans. Here we describe the development and testing of novel …

A novel MVA vectored Chikungunya virus vaccine elicits protective immunity in mice

J Weger-Lucarelli, H Chu, MT Aliota… - PLoS neglected …, 2014 - journals.plos.org
Background Chikungunya virus (CHIKV) is a re-emerging arbovirus associated with febrile
illness often accompanied by rash and arthralgia that may persist for several years …

Development of vaccines for chikungunya fever

JH Erasmus, SL Rossi… - The Journal of infectious …, 2016 - academic.oup.com
Chikungunya fever, an acute and often chronic arthralgic disease caused by the mosquito-
borne chikungunya virus (CHIKV), has reemerged since 2004 to cause millions of cases …

Infectious chikungunya virus (CHIKV) with a complete capsid deletion: a new approach for a CHIKV vaccine

YN Zhang, CL Deng, JQ Li, N Li, QY Zhang… - Journal of …, 2019 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes epidemics of
debilitating disease worldwide. Currently, there are no licensed vaccines or antivirals …

Cross-protective immunity against o 'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

CD Partidos, J Paykel, J Weger, EM Borland… - Vaccine, 2012 - Elsevier
Emerging mosquito-borne alphavirus infections caused by chikungunya virus (CHIKV) or o
'nyong-nyong virus (ONNV) are responsible for sporadic and sometimes explosive urban …