The shift in ocular dominance (OD) of binocular neurons induced by monocular deprivation
is the canonical model of synaptic plasticity confined to a postnatal critical period …

Brief monocular deprivation (≤ 3 d) induces a rapid shift in the ocular dominance of
binocular neurons in the juvenile rodent visual cortex but is ineffective in adults. Here, we …

Over the last 50 years, research into the developmental plasticity of the visual cortex has led
to a growing understanding of first the causes and then of the underlying cellular …

During development, cortical plasticity is associated with the rearrangement of excitatory
connections. While these connections become more stable with age, plasticity can still be …

Postnatal cortical circuit development is characterized by windows of heightened plasticity
that contribute to the acquisition of mature connectivity and function. What drives the …

Sensory experience profoundly shapes neural circuitry of juvenile brain. Although the visual
cortex of adult rodents retains a capacity for plasticity in response to monocular visual …

Amblyopia is a visual impairment secondary to abnormal visual experience (eg, strabismus,
anisometropia, form deprivation) during early childhood that cannot be corrected …

Amblyopia is the condition in which reduced visual function exists despite full optical
correction and an absence of observable ocular pathology. Investigation of the underlying …

Although historically, treatment of amblyopia has been recommended prior to closure of a
critical window in visual development, the existence and duration of that critical window is …

During the past 20 years, basic science has shown that there are different critical periods for
different visual functions during the development of the visual system. Visual functions …