Exploring potential biomarkers and therapeutic targets of long COVID-associated inflammatory cardiomyopathy

P Qi, M Huang, H Zhu - Frontiers in Medicine, 2023 - frontiersin.org
Background The negative impact of long COVID on social life and human health is
increasingly prominent, and the elevated risk of cardiovascular disease in patients …

Exploring potential biomarkers and molecular mechanisms of ischemic cardiomyopathy and COVID-19 comorbidity based on bioinformatics and systems biology

S Luo, X Zhang, X Xiao, W Luo, Z Yang, S Tang… - International Journal of …, 2023 - mdpi.com
Cardiovascular complications combined with COVID-19 (SARS-CoV-2) lead to a poor
prognosis in patients. The common pathogenesis of ischemic cardiomyopathy (ICM) and …

Cardiac inflammation in COVID-19: Lessons from heart failure

SD Unudurthi, P Luthra, RJC Bose, JR McCarthy… - Life sciences, 2020 - Elsevier
Cardiovascular disease (CVD) is the most common co-morbidity associated with COVID-19
and the fatality rate in COVID-19 patients with CVD is higher compared to other …

Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart

H Bräuninger, B Stoffers, ADE Fitzek… - Cardiovascular …, 2022 - academic.oup.com
Aims Cardiac involvement in COVID-19 is associated with adverse outcome. However, it is
unclear whether cell-specific consequences are associated with cardiac SARS-CoV-2 …

Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation

S Dai, T Cao, H Shen, X Zong, W Gu, H Li… - Journal of Translational …, 2023 - Springer
Abstract Background SARS-CoV-2, the pathogen of COVID-19, is a worldwide threat to
human health and causes a long-term burden on the cardiovascular system. Individuals with …

COVID-19 severity potentially modulated by cardiovascular-disease-associated immune dysregulation

AC Lee, G Castaneda, WT Li, C Chen, N Shende… - Viruses, 2021 - mdpi.com
Patients with underlying cardiovascular conditions are particularly vulnerable to severe
COVID-19. In this project, we aimed to characterize similarities in dysregulated immune …

Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium

R Zhang, X Chen, W Zuo, Z Ji, Y Qu, Y Su, M Yang… - …, 2022 - Taylor & Francis
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can target
cardiomyocytes (CMs) to directly invade the heart resulting in high mortality. This study aims …

Unraveling the molecular crosstalk and immune landscape between COVID-19 infections and ischemic heart failure comorbidity: New insights into diagnostic …

G Wu, J Zhou, H Ren, Y Qin, D Qian, Q Hu, P Xu, T Yu… - Cellular …, 2023 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19), resulting from severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), remains a persistent global health …

Molecular mechanisms of cardiac injury associated with myocardial SARS-CoV-2 infection

X Liu, L Lou, L Zhou - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has spread around the world. The development of cardiac …

A bioinformatics approach for identifying potential molecular mechanisms and key genes involved in COVID-19 associated cardiac remodeling

H Ceylan - Gene reports, 2021 - Elsevier
Abstract In 2019 coronavirus disease (COVID-19), whose main complication is respiratory
involvement, different organs may also be affected in severe cases. However, COVID-19 …