The CH bond of aldehyde can be cleaved by a transition metal complex to give acylmetal
hydride. If subsequent decarbonylation is suppressed, hydroacylation of olefin can proceed …

In this review, transition‐metal‐catalyzed intermolecular hydroacylation, which is a direct
synthetic protocol generating ketones from aldehydes and unsaturated hydrocarbons, will …

The catalytic activation and subsequent functionalization of CH bonds is an attractive goal
for synthetic chemists, with reactions that employ low catalyst loadings and result in the …

Activation of the aldehydic carbon-hydrogen bond by transition-metal complexes has
especially received interest because of its relevance to organic synthesis through …

The hydroacylation of multiple bonds is a highly versatile reaction that uses abundant
starting materials such as alkenes and aldehydes for the formation of valuable ketone …

Prior examples of hydroacylation to form six-and seven-membered ring ketones require
either embedded chelating groups or other substrate design strategies to circumvent …

We report the first intermolecular NHC-catalyzed hydroacylation of electron-neutral olefins.
Treatment of aromatic aldehydes with cyclopropenes under mild conditions affords valuable …

The addition of an aldehyde across the C. C multiple bond of an alkene, an alkyne, or an
allene delivers a synthetically useful ketone-containing product. The most widely used …

Conspectus By using transition metal catalysts, chemists have altered the “logic of chemical
synthesis” by enabling the functionalization of carbon–hydrogen bonds, which have …

β-Thioacetal-substituted aldehydes, which are conveniently prepared from the
corresponding ynals, can be combined with a range of alkynes or electron-poor alkenes to …