Facile synthesis of halogenated spiroketals via a tandem iodocyclization

J Wang, HT Zhu, YX Li, LJ Wang, YF Qiu, ZH Qiu… - Organic …, 2014 - ACS Publications
A strategy for the synthesis of spiroketal compounds through a tandem iodocyclization of 1-
(2-ethynylphenyl)-4-hydroxybut-2-yn-1-one derivatives is presented. This reaction could …

Nickel-mediated stereocontrolled synthesis of spiroketals via tandem cyclization–coupling of β-bromo ketals and aryl iodides

Y Peng, XB Xu, J Xiao, YW Wang - Chemical Communications, 2014 - pubs.rsc.org
Nickel-mediated stereocontrolled synthesis of spiroketals via tandem cyclization–coupling
of β-bromo ketals and aryl iodides - Chemical Communications (RSC Publishing) DOI:10.1039/C3CC47780K …

Indium-catalyzed synthesis of benzannulated spiroketals by intramolecular double hydroalkoxylation of ortho-(hydroxyalkynyl) benzyl alcohols

R Pérez-Guevara, LA Sarandeses… - Organic Chemistry …, 2022 - pubs.rsc.org
The novel indium-catalyzed synthesis of benzannulated spiroketals by a double
intramolecular hydroalkoxylation reaction of o-(hydroxyalkynyl) benzyl alcohols is reported …

Pd (II)-catalyzed tandem heterocyclization of 1-(1-alkynyl) cyclopropyl oxime derivatives for the synthesis of functionalized pyrroles

D Pan, Y Wei, M Shi - Organic letters, 2016 - ACS Publications
An efficient approach for the synthesis of highly functionalized pyrroles has been developed
by a Pd (TFA) 2-catalyzed tandem heterocyclization of 1-(1-alkynyl) cyclopropyl oxime …

Iodobenzene catalysed synthesis of spirofurans and benzopyrans by oxidative cyclisation of vinylogous esters

M Ngatimin, R Frey, C Andrews, DW Lupton… - Chemical …, 2011 - pubs.rsc.org
Vinylogous esters bearing para or metamethoxy benzyl groups undergo oxidative
cyclisation with 5–20 mol% iodobenzene and m-CPBA to give spirofuran or benzopyran …

A two step synthesis of spiroketals

P Pale, J Chuche - Tetrahedron letters, 1988 - Elsevier
Tetrahedron Letters,Vol.29,No.24,pp 2947-2950,1988 $3.00 + -00 Printed in Great Britain
Pergamon Press plc P. PALE, J. CHUCHE La Page 1 Tetrahedron Letters,Vol.29,No.24,pp …

Diastereoselective Synthesis of Six‐Membered Carbocyclic Spirooxindoles via 6π‐Electrocyclization of 3‐Dienylidene‐2‐ oxindoles

KH Kim, HR Moon, J Lee, J Kim… - Advanced Synthesis & …, 2015 - Wiley Online Library
The Wittig reaction of isatin derivatives with Morita–Baylis–Hillman bromides of
cinnamaldehydes afforded 3‐dienylidene‐2‐oxindoles. These trienes were converted into …

Efficient synthesis of spiro diheterocycles via multi-component dicyclization reaction

L Wang, P Zhao, S Li, Y Ma, P Zhang… - Organic & Biomolecular …, 2022 - pubs.rsc.org
A facile synthetic protocol for the preparation of spiro diheterocycles from easily available
2′-aminoacetophenones, isocyanates and 1, 4-benzoquinones or quinone monoimines …

Palladium‐Catalyzed Regioselective Domino Spirocyclization of Carbamoyl Chlorides with Alkynes and Benzynes

C Wang, W Zhao, X Wu, J Qu… - Advanced Synthesis & …, 2020 - Wiley Online Library
A palladium‐catalyzed domino spiro‐cyclization of carbamoyl chlorides with alkynes and
benzynes, involving intramolecular C− H activation to afford valuable oxindole scaffolds …

Construction of pyrazole fused spiroketals by a (3+ 2) annulation reaction

W Zhang, X Wei, Y Wang, Y Huang, S Nawaz… - Organic Chemistry …, 2022 - pubs.rsc.org
A stereoselective (3+ 2) annulation process between 4-bromo pyrazolones and benzofuran-
derived azadienes was developed. A series of novel pyrazole fused spiroketals were …