With the recent success of genome-wide association studies (GWAS), a wealth of association data has been accomplished for more than 200 complex diseases/traits …
CP Yang, X Li, Y Wu, Q Shen, Y Zeng, Q Xiong… - Nature …, 2018 - nature.com
Recent genome-wide association studies (GWAS) have identified multiple risk loci that show strong associations with schizophrenia. However, pinpointing the potential causal genes at …
H Chang, X Cai, HJ Li, WP Liu, LJ Zhao, CY Zhang… - Biological …, 2021 - Elsevier
Background Genome-wide association studies (GWASs) have reported hundreds of genomic loci associated with schizophrenia, yet identifying the functional risk variations is a …
Y Huo, S Li, J Liu, X Li, XJ Luo - Nature communications, 2019 - nature.com
Genome-wide association studies (GWASs) have identified over 180 independent schizophrenia risk loci. Nevertheless, how the risk variants in the reported loci confer …
J Liu, S Li, X Li, W Li, Y Yang, S Guo, L Lv, X Xiao… - BMC medicine, 2021 - Springer
Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in …
M Ayalew, H Le-Niculescu, DF Levey, N Jain… - Molecular …, 2012 - nature.com
We have used a translational convergent functional genomics (CFG) approach to identify and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …
Schizophrenia is a severe mental disorder with a large genetic component. Recent genome- wide association studies (GWAS) have identified many schizophrenia-associated common …
D Schijven, D Kofink, V Tragante, M Verkerke… - Schizophrenia …, 2018 - Elsevier
Large-scale genome-wide association studies (GWAS) have implicated many low- penetrance loci in schizophrenia. However, its pathological mechanisms are poorly …
Background While hybridization based analysis of the cortical transcriptome has provided important insight into the neuropathology of schizophrenia, it represents a restricted view of …