Bromo-or Methoxy-Group-Promoted Umpolung Electron Transfer Enabled, Visible-Light-Mediated Synthesis of 2-Substituted Indole-3-glyoxylates

A Vidyasagar, J Shi, P Kreitmeier, O Reiser - Organic letters, 2018 - ACS Publications
A visible-light-mediated radical tandem cyclization of ortho-isocyano-α-bromo cinnamates to
2-substituted indole-3-glyoxylates is achieved by formation of both C–C/C–S and C–O …

Cascade cyclization for the synthesis of indolo [2, 1-α] isoquinoline derivatives via visible-light-induced halogen-atom-transfer (XAT) and hydrogen-atom-transfer (HAT …

N Ma, L Guo, ZJ Shen, D Qi, C Yang… - Organic & Biomolecular …, 2022 - pubs.rsc.org
A transition metal-free photoredox cascade cyclization is herein reported. In this protocol,
sustainable visible light was used as the energy source and organic light-emitting molecule …

Controlled Photochemical Synthesis of Substituted Isoquinoline-1,3,4(2H)-triones, 3-Hydroxyisoindolin-1-ones, and Phthalimides via Amidyl Radical Cyclization …

MB Reddy, K Prasanth, R Anandhan - Organic Letters, 2022 - ACS Publications
We report a controlled radical cyclization cascade of isoquinoline-1, 3, 4 (2 H)-triones, 3-
hydroxyisoindolin-1-ones, and phthalimides from o-alkynylated benzamides by metal-free …

Tandem cyclisation of vinyl radicals: a sustainable approach to indolines utilizing visible-light photoredox catalysis

SK Pagire, O Reiser - Green Chemistry, 2017 - pubs.rsc.org
A tin-free method for the synthesis of substituted indolines has been developed generating
vinyl radicals by visible-light-promoted photocatalysis in a reductive quenching cycle. This …

Controllable synthesis of benzoxazinones and 2-hydroxy-3-indolinones by visible-light-promoted 5-endo-dig N-radical cyclization cascade

TD Tan, TY Zhai, BY Liu, L Li, PC Qian, Q Sun… - Cell Reports Physical …, 2021 - cell.com
In recent years, significant advances have been made on photoredox-catalyzed N-radical
addition to CC unsaturated bond via NH bond cleavage. However, these N-centered radical …

Photoredox‐Catalyzed Carbon Radical Generation from α‐Keto‐N,O‐acetals: Synthesis of Functionalized Azepino[1,2‐a]indoles and Azepino[1,2‐a]furo[3,2‐b] …

P Seefeldt, A Villinger… - Advanced Synthesis & …, 2024 - Wiley Online Library
Abstract C10a‐Acetoxylated perhydroazepino [1, 2‐a]‐indoles, accessible via visible light‐
mediated sensitized photooxygenation of cyclo‐hepta [b] indoles, are precursors to …

Visible‐Light‐Mediated Dearomatization/Cyanation Cascade Reaction of Indoles: Access to Highly Functionalized Spiro‐γ‐lactam Indolines with Two Contiguous …

Q Wang, Y Qu, Q Xia, H Song, H Song… - Advanced Synthesis …, 2018 - Wiley Online Library
A protocol for visible‐light‐induced radical dearomatization/cyanation cascade reaction of
indole derivatives is reported. This protocol provides straightforward access to gem …

Controllable Synthesis of Cyclopenta[b]indolines via Photocatalytic Fluoroalkylative Radical Cyclization Cascade of Ynamides

J Li, Y Zhou, J Luo, H Chen, H Qi, H Zheng… - Organic Letters, 2024 - ACS Publications
A de novo method for direct construction of cyclopenta [b] indolines via a photocatalytic
fluoroalkylative radical cyclization cascade of ynamides has been established, which …

Photoredox-Catalyzed Alkylarylation of N-Aryl Bicyclobutyl Amides with α-Carbonyl Alkyl Bromides: Access to 3-Spirocyclobutyl Oxindoles

JH Fan, J Yuan, PF Xia, J Zhou, LJ Zhong… - Organic …, 2024 - ACS Publications
A visible-light-induced radical alkylarylation of N-aryl bicyclobutyl amides with α-carbonyl
alkyl bromides for the synthesis of functionalized 3-spirocyclobutyl oxindoles is described in …

Visible-light-induced alkoxycarbonylation/cyclization of 1, 7-enynes: synthesis of dihydropyranones containing all-carbon quaternary centers

JQ Chen, Q Chen, B Chen, J Wu - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
A direct photoredox catalyzed radical-triggered tandem cyclization of 1, 7-enynes with
alkyloxalyl chlorides is developed. With this approach, a variety of dihydropyranones …