Therapeutic role of immunomodulators during the COVID-19 pandemic–a narrative review

H Al-Hajeri, F Baroun, F Abutiban… - Postgraduate …, 2022 - Taylor & Francis
The emergency state caused by COVID-19 saw the use of immunomodulators despite the
absence of robust research. To date, the results of relatively few randomized controlled trials …

Immunomodulatory-based therapy as a potential promising treatment strategy against severe COVID-19 patients: A systematic review

M Razmi, F Hashemi, E Gheytanchi… - International …, 2020 - Elsevier
The global panic of the novel coronavirus disease 2019 (COVID-19) triggered by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an urgent requirement …

Pharmaco-immunomodulatory therapy in COVID-19

JG Rizk, K Kalantar-Zadeh, MR Mehra, CJ Lavie… - Drugs, 2020 - Springer
The severe acute respiratory syndrome coronavirus 2 associated coronavirus disease 2019
(COVID-19) illness is a syndrome of viral replication in concert with a host inflammatory …

Immunomodulatory drugs in the management of SARS-CoV-2

DR Burrage, S Koushesh, N Sofat - Frontiers in immunology, 2020 - frontiersin.org
With the onset of the global pandemic in 2020 of Severe Acute Respiratory Syndrome
Coronavirus-2 (SARS-CoV-2), there has been increasing research activity around certain …

Current and emerging immunomodulators for treatment of SARS-CoV2 infection (COVID-19)

MW McCarthy - Expert Opinion on Pharmacotherapy, 2022 - Taylor & Francis
ABSTRACT Introduction SARS-CoV-2, the virus that causes COVID-19, elicits a variety of
host responses ranging from asymptomatic or mild illness in most people, to severe disease …

[HTML][HTML] Choosing immunomodulating therapies for the treatment of COVID-19: recommendations based on placebo-controlled trial evidence

DA Sweeney, SM Lobo, P Póvoa, AC Kalil - Clinical Microbiology and …, 2024 - Elsevier
Background Immunomodulatory therapy has been extensively studied in randomized
clinical trials for the treatment of patients hospitalized for COVID-19 with inconsistent …

Immunomodulatory therapies for the treatment of SARS-CoV-2 infection: an update of the systematic literature review to inform EULAR points to consider

A Alunno, A Najm, X Mariette, G De Marco, J Emmel… - RMD open, 2021 - rmdopen.bmj.com
Objective To update the EULAR 2020 systematic literature review (SLR) on efficacy and
safety of immunomodulatory agents in SARS-CoV-2 infection. Methods As part of a EULAR …

Advances in immunotherapy for COVID-19: A comprehensive review

M Masoomikarimi, B Garmabi, J Alizadeh… - International …, 2021 - Elsevier
COVID-19 is an acute respiratory syndrome caused by SARS-COV-2 which has now
become a huge pandemic worldwide. The immunopathogenesis of COVID-19 has been …

[HTML][HTML] Immunomodulators for immunocompromised patients hospitalized for COVID-19: a meta-analysis of randomized controlled trials

II Siempos, AC Kalil, D Belhadi, VC Veiga… - …, 2024 - thelancet.com
Background Although immunomodulators have established benefit against the new
coronavirus disease (COVID-19) in general, it is uncertain whether such agents improve …

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

J Alijotas-Reig, E Esteve-Valverde, C Belizna… - Autoimmunity …, 2020 - Elsevier
Abstract Severe Acute Respiratory Syndrome related to Coronavirus-2 (SARS-CoV-2),
coronavirus disease-2019 (COVID-19) may cause severe illness in 20% of patients. This …