Matrix metalloproteinases (MMPs) emerge as modulators of neuropathic pain. Because
myelin protects Aβ afferents from ectopic hyperexcitability and nociception from innocuous …

Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced in Schwann
cells hours after peripheral nerve injury and controls axonal degeneration and macrophage …

Neuropathic pain affects millions of people globally and could be a disease on its own right.
Current treatments focus on blocking neurotransmission and have resulted in limited …

Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced hours after
injury to peripheral nerve. This study shows that MMP-9 gene deletion and neutralization …

Matrix metalloproteinases (MMPs) are a family of endopeptidases that degrade extracellular
matrix components. Membrane-type 5 MMP (MT5-MMP/MMP-24) was identified as neuron …

This review will focus on matrix metalloproteinases (MMPs) and their inhibitors in the context
of spinal cord injury (SCI). MMPs have a specific cellular and temporal pattern of expression …

Background In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9
performs essential functions in the acute response to injury. Whether MMP-9 activity …

Neuronal glial antigen 2 (NG2) is an integral membrane chondroitin sulfate proteoglycan
expressed by vascular pericytes, macrophages (NG2-Mφ), and progenitor glia of the …

Abstract Treatment of neuropathic pain, triggered by multiple insults to the nervous system,
is a clinical challenge because the underlying mechanisms of neuropathic pain …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in both injury
and repair mechanisms in the CNS. Pharmacological blockade of MMPs, limited to the first …