Valvular heart disease accounts for over 20 000 deaths and 90 000 hospitalizations yearly
in the United States. Myxomatous valve disease (MVD) is the most common disease of the …

Canine myxomatous mitral valve disease (MMVD) is similar to Barlow's form of MMVD in
humans. These valvulopathies are complex, with varying speeds of progression. We …

Degenerative mitral valve disease (DMVD), which includes the syndromes of mitral valve
prolapse (MVP) and flail leaflet, is a common valvular condition which can be complicated …

Background Although it is well known that myxomatous mitral valve disease stage B2
(MMVD stage B2) is predominantly characterized by ECM remodeling of the mitral valve …

Objective—To evaluate global genome expression patterns of mitral valve tissues from dogs
with degenerative mitral valve disease (DMVD). Sample Population—Anterior mitral valve …

Myxomatous mitral valve disease is the single most important mitral valve disease in both
dogs and humans. In the case of the dog it is ubiquitous, such that all aged dogs will have …

Myxomatous mitral valve disease (MMVD) is the most common acquired canine
cardiovascular disease and shares many similarities with human mitral valvulopathies …

A precise mixture of extracellular matrix (ECM) secreted by valvular cells forms a scaffold
that lends the heart valve the exact mechanical and tensile strength needed for accurate …

Chronic valve disease (CVD) is the most common clinically significant heart disease of dogs,
affecting 20 to 40% of dogs. The aim of this study was to evaluate the serum protein profile of …

Myxomatous degenerative mitral valve disease (MMVD) is a common heart disease in dogs.
Although several morphological similarities occur between human and canine MMVD …