Storm at the time of corona: a glimpse at the current understanding and therapeutic opportunities of the SARS-CoV-2 cytokine storm

M Torabi-Rahvar, N Rezaei - Current Pharmaceutical Design, 2021 - ingentaconnect.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to severe
disease in some cases, leading to acute respiratory distress syndrome, multi-organ failure …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …

[HTML][HTML] Severe acute respiratory syndrome coronavirus-2 induces cytokine storm and inflammation during coronavirus disease 19: perspectives and possible …

F Mannino, A Bitto, N Irrera - Frontiers in Pharmacology, 2020 - frontiersin.org
The new coronavirus outbreak was first identified in Wuhan, China, in December 2019, and
has turned out to be a global health emergency, affecting millions of people worldwide …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

[HTML][HTML] The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

Cytokine storm is the cryptic killer behind coronavirus disease-2019 infections, review of the current evidence to identify therapeutic options

D Alrahmany, IM Ghazi - Reviews and Research in Medical …, 2021 - journals.lww.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)(coronavirus disease 2019)
is currently a rapidly disseminating viral infection that turned into a global pandemic with …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Cytokines and COVID-19: friends or foes?

M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
The cytokine storm following sepsis has been proven to be an important mechanism for
triggering acute respiratory distress syndrome, which is a fatal uncontrolled systemic …

[HTML][HTML] Should we unstress SARS-CoV-2 infected cells?

F Csukasi, G Rico, J Becerra, I Duran - Cytokine & growth factor …, 2020 - ncbi.nlm.nih.gov
SARS-CoV-2 has caused an unprecedented challenge to the medical and scientific
communities around the world. For weeks, we have struggled to figure out why some …