Major depressive disorder (MDD) is a complex, heritable psychiatric disorder. Advanced
statistical genetics for genome-wide association studies (GWASs) have suggested that the …

Background Identifying the phenotypic manifestations of increased genetic liability for
depression (MDD) and bipolar disorder (BD) can enhance understanding of their aetiology …

Multiple genetic and environmental factors influence the risk for both major depression and
alcohol/substance use disorders. In addition, there is evidence that these illnesses share …

Background. Previous studies suggest that the relationship between genetic risk and
depression may be moderated by stressful life events (SLEs). The goal of this study was to …

Compared with men, female accounts for a larger proportion of patients with depression.
Behavioral genetics researches find gender differences in genetic underpinnings of …

BackgroundIt has been well established that both genes and non-shared environment
contribute substantially to the underlying aetiology of major depressive disorder (MDD). A …

A genome scan was performed on the first phase sample of the Genetics of Recurrent Early-
Onset Depression (GenRED) project. The sample consisted of 297 informative families …

Major depression is the commonest psychiatric disorder and in the US has the greatest
impact of all biomedical diseases on disability. Here we review evidence of the genetic …

BACKGROUND: Despite overwhelming evidence that major depression is highly heritable,
recent studies have localized only a single depression-related locus reaching genome-wide …

Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …