The frequency of hereditary nonpolyposis colorectal cancer was evaluated in a group of
colorectal cancer patients under age 50 diagnosed in southern Alberta between 1973 and …

Segregation analysis of eleven families comprising 2762 individuals indicated compatibility
of the data with segregation of a major autosomal dominant gene for hereditary …

Previous survival studies suggested a better prognosis of hereditary nonpolyposis colorectal
cancer (HNPCC) patients compared with the sporadic counterpart. In the present study we …

Pathological characteristics of colorectal cancers and adenomas developing in 140
members of 34 Hereditary Non-Polyposis Colorectal Cancer (HNPCC) families are …

Hereditary non‐polyposis colorectal cancer (HNPCC) is an autosomal dominant disorder
characterized by susceptibility to large‐bowel cancer, frequently with early onset and …

PURPOSE: An increased incidence of multiple (synchronous and metachronous) colorectal
carcinomas has been reported in hereditary nonpolyposis colorectal cancer. This review …

The frequency of hereditary colorectal carcinoma was evaluated in a study group consisting
of all colorectal carcinoma patients (n= 468) diagnosed in one Finnish county (0.25 million …

During its second meeting at Amsterdam in 1990, the International Collaborative Group on
Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC) decided to carry out a pilot study …

Members of colon cancer-prone nonpolyposis families who had multiple primary malignant
tumors were analyzed to determine the frequencies, locations, and stages of their cancers …

Background Previous reports have indicated that 5–13 per cent of colorectal cancer is
hereditary. However, the proportion of cases arising as a result of mutations in the hereditary …