Efficient system wide metabolic pathway comparisons in multiple microbes using genome to KEGG orthology (G2KO) pipeline tool

C Joshi, S Sharma, N MacKinnon… - Interdisciplinary Sciences …, 2020 - Springer
Abstract Comparison of system-wide metabolic pathways among microbes provides
valuable insights of organisms' metabolic capabilities that can further assist in rationally …

MicrobesFlux: a web platform for drafting metabolic models from the KEGG database

X Feng, Y Xu, Y Chen, YJ Tang - BMC systems biology, 2012 - Springer
Background Concurrent with the efforts currently underway in mapping microbial genomes
using high-throughput sequencing methods, systems biologists are building metabolic …

[PDF][PDF] CARMEN-Comparative analysis and in silico reconstruction of organism-specific metabolic networks

J Schneider, FJ Vorhölter, E Trost, J Blom, YR Musa… - Genet Mol …, 2010 - academia.edu
New sequencing technologies provide ultra-fast access to novel microbial genome data. For
their interpretation, an efficient bioinformatics pipeline that facilitates in silico reconstruction …

Automated generation of genome-scale metabolic draft reconstructions based on KEGG

E Karlsen, C Schulz, E Almaas - BMC bioinformatics, 2018 - Springer
Background Constraint-based modeling is a widely used and powerful methodology to
assess the metabolic phenotypes and capabilities of an organism. The starting point and …

[HTML][HTML] KEMET–A python tool for KEGG Module evaluation and microbial genome annotation expansion

M Palù, A Basile, G Zampieri, L Treu, A Rossi… - Computational and …, 2022 - Elsevier
Background The rapid accumulation of sequencing data from metagenomic studies is
enabling the generation of huge collections of microbial genomes, with new challenges for …

[HTML][HTML] Pathway tools management of pathway/genome data for microbial communities

PD Karp, S Paley, M Krummenacker… - Frontiers in …, 2022 - frontiersin.org
The Pathway Tools (PTools) software provides a suite of capabilities for storing and
analyzing integrated collections of genomic and metabolic information in the form of …

MPA_Pathway_Tool: user-friendly, automatic assignment of microbial community data on metabolic pathways

D Walke, K Schallert, P Ramesh, D Benndorf… - International journal of …, 2021 - mdpi.com
Taxonomic and functional characterization of microbial communities from diverse
environments such as the human gut or biogas plants by multi-omics methods plays an ever …

Predicting metabolic modules in incomplete bacterial genomes with MetaPathPredict

D Geller-McGrath, KM Konwar, VP Edgcomb… - Elife, 2024 - elifesciences.org
The reconstruction of complete microbial metabolic pathways using 'omics data from
environmental samples remains challenging. Computational pipelines for pathway …

Genome-scale reconstructions to assess metabolic phylogeny and organism clustering

C Schulz, E Almaas - PLoS One, 2020 - journals.plos.org
Approaches for systematizing information of relatedness between organisms is important in
biology. Phylogenetic analyses based on sets of highly conserved genes are currently the …

MetaPathPredict: A machine learning-based tool for predicting metabolic modules in incomplete bacterial genomes

D Geller-McGrath, KM Konwar, VP Edgcomb… - BioRxiv, 2022 - biorxiv.org
The reconstruction of complete microbial metabolic pathways using 'omics data from
environmental samples remains challenging. Computational pipelines for pathway …